Skip to Main Content

Paper Details

The role of FXR and TGR5 in reversing and preventing progression of Western diet-induced hepatic steatosis, inflammation, and fibrosis in mice.
J Biol Chem
11
2022
FXR, G protein-coupled receptor TGR5, INT-767, NASH, Nonalcoholic steatohepatitis, PGC, PGC-1, SIRT1, SIRT3, TGR5, WD, bile acid, bile acids, cholesterol, chronic liver disease, fatty acid, fibrosis, hepatic steatosis, inflammation, liver inflammation, metabolic syndrome, mice, nuclear receptor farnesoid X receptor, obesity, p-AMPK, type 2 diabetes
Author NameAffiliation
David J OrlickyUniversity of Colorado AMC
Stephen M HewittNational Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health
Stephen M HewittNational Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health
Jeffrey B KoppNational Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health
Frank J GonzalezNational Cancer Institute, National Institutes of Health
  • 1 - 5

Datasets

Release 1.2