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Paper Details

A compartmentalized phosphoinositide signaling axis at cilia is regulated by INPP5E to maintain cilia and promote Sonic Hedgehog medulloblastoma.
Oncogene
36
2017
AKT, GPR161, GSK3, HA-INPP5E, INPP5E, INPP5E mRNA, Inpp5e, Inpp5e-null tumor cells, PI3-kinase, PtdIns(3,4,5)P3, PtdIns(4,5)P2, SHH, SHH medulloblastoma, SHH-dependent medulloblastoma, Smoothened, Sonic Hedgehog, Sonic Hedgehog medulloblastoma, cancer, cultured Inpp5e-null tumor cells, human, inositol polyphosphate, inositol polyphosphate 5-phosphatase, malignant paediatric brain tumor, medulloblastoma, medulloblastomas, murine, pAKT, pGSK3, phosphoinositide, phosphoinositide (PI) 3-kinase, primary, primary cilia, tumor, tumor cell, tumor cells
Author NameAffiliation
Vijay RamaswamyHospital for Sick Children
Marc RemkeThe Arthur and Sonia Labatt Brain Tumor Research Centre, Hospital for Sick Children
David N WatkinsThe Kinghorn Cancer Centre, Garvan Institute of Medical Research
David N WatkinsSt. Vincent's Clinical School
David N WatkinsSt Vincent's Hospital
Brandon J WainwrightInstitute for Molecular Bioscience, The University of Queensland
Michael D TaylorThe Arthur and Sonia Labatt Brain Tumor Research Centre, Hospital for Sick Children
Michael D TaylorThe Arthur and Sonia Labatt Brain Tumor Research Centre, Hospital for Sick Children
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