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Paper Details

Inhibition of the type 1 diabetes candidate gene PTPN2 aggravates TNF-α-induced human beta cell dysfunction and death.
5
2023
BIM, Bcl-2-like protein 2, C-peptide, EndoC-H1 cells, Hoechst 33342, IFN, IFN-, JNK1, JNK3, N, PTPN2, PTPN2 polymorphisms, TNF, TNF-, TNF-,, beta cell, c-Jun N-terminal kinase (JNK)1, human, human beta cells, human cell model, induced pluripotent stem cell (iPSC)-derived islet-like cells, mRNA, pancreatic beta cell, people, propidium iodide, siRNAs, type, type 1 diabetes, type 1 diabetes mellitus, type I IFNs, tyrosine
Author NameAffiliation
Lorella MarselliUniversity of Pisa
Miriam CnopULB Center for Diabetes Research, Universite Libre De Bruxelles
Miriam CnopErasmus Hospital, Universite Libre de Bruxelles
Piero MarchettiUniversity of Pisa
Decio L EizirikULB Center for Diabetes Research, Universite Libre De Bruxelles
Decio L EizirikWEL Research Institute
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