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Paper Details

Discovery of IACS-9439, a Potent, Exquisitely Selective, and Orally Bioavailable Inhibitor of CSF1R.
Journal of Medicinal Chemistry
11
2020
CSF1, CSF1R, IACS-9439, M1, MC38, PANC02 syngeneic tumor models, TAMs, Tumor, Tumor-associated macrophages, cancers, human, immune-suppressive M2 TAMs, macrophage, macrophages, tumor, tumor cells, type III kinase
Author NameAffiliation
Jeffrey J KovacsUniversity of Texas MD Anderson Cancer Center
Timothy P HeffernanUniversity of Texas MD Anderson Cancer Center
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Release 1.2