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The antileukemic activity of decitabine upon PML/RARA-negative AML blasts is supported by all-trans retinoic acid: in vitro and in vivo evidence for cooperation.
Blood Cancer J
5
2022
AML, AML cell lines, ATRA, CYP26A1, CYP26A1, GBP4, and LYZ genes, DAC, GBP4, HIC1, HIC1,, LYZ genes, MOLM, MOLM-13, PML, PML/RARA-negative AML blasts, RARA, RNA, TP53, U937, all-trans retinoic acid, chromatin, commonly regulated transcripts, decitabine, patients, peripheral blood blasts, retinoic acid, retinoic acid response elements, transposable elements
Author NameAffiliation
Lars FeuerbachGerman Cancer Research Center (DKFZ)
Benedikt BrorsGerman Cancer Research Center (DKFZ)
Benedikt BrorsNational Center for Tumor Diseases (NCT)
Benedikt Brors
Benedikt BrorsGerman Cancer Research Center (DKFZ)
Benedikt Brors
Benedikt BrorsNational Center for Tumor Diseases (NCT)
Christoph PlassGerman Cancer Research Center (DKFZ)
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