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Paper Details

Antigen-independent activation enhances the efficacy of 4-1BB-costimulated CD22 CAR T cells.
Nat Med
81
2021
4-1BB, ALL, B cell acute lymphoblastic leukemia, B-lineage cells, CAR, CAR T cell, CAR antigen-binding domain, CAR constructs, CARs, CD19, CD19- disease, CD19-directed chimeric antigen receptor (CAR) T cells, CD22, CD22 CAR, CD22 CAR T cells, CD28, T cells, amino acid, chimeric, patients, pro-inflammatory genes
Author NameAffiliation
David M BarrettThe Children's Hospital of Philadelphia
David M BarrettPerelman School of Medicine at the University of Pennsylvania
Xueqing Maggie LuPenn Institute for Biomedical Informatics, Perelman School of Medicine at the University of Pennsylvania
Jessica PerazzelliThe Children's Hospital of Philadelphia
Daron M StandleyResearch Institute for Microbial Diseases
Daron M StandleyResearch Institute for Microbial Diseases
Stephan A GruppThe Children's Hospital of Philadelphia
Carl H JunePerelman School of Medicine at the University of Pennsylvania
Carl H JuneCenter for Cellular Immunotherapies, Perelman School of Medicine at the University of Pennsylvania
Carl H JunePerelman School of Medicine at the University of Pennsylvania
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