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Paper Details

Multimodal perturbation analyses of cyclin-dependent kinases reveal a network of synthetic lethalities associated with cell-cycle regulation and transcriptional regulation.
Sci Rep
1
2023
CDK, CDK1/7/9/12, CDK4/6, CDK6, CDKs, Cas9, PRMT5, cancer, cell states, cyclin, cyclin-dependent kinases, mRNA
Cell Cycle, Cell Cycle Checkpoints, Humans, Neoplasms, Protein-Arginine N-Methyltransferases
Author NameAffiliation
Kyle FordUniversity of California San Diego
Brenton MunsonUniversity of California San Diego
Brenton MunsonUniversity of California San Diego
Samson H FongUniversity of California San Diego
Samson H FongUniversity of California San Diego
Rebecca PanwalaUniversity of California San Diego
Wai K ChuUniversity of California San Diego
Joseph RainaldiUniversity of California San Diego
Joseph RainaldiUniversity of California San Diego
Nongluk PlongthongkumUniversity of California San Diego
Vinayagam Arunachalam
Jarek Kostrowicki
Dario MeluzziUniversity of California San Diego
Jason F KreisbergUniversity of California San Diego
Kristen Jensen-Pergakes
Todd VanArsdale
Thomas Paul
Pablo TamayoUniversity of California San Diego
Kun ZhangUniversity of California San Diego
Kun ZhangUniversity of California San Diego
Jadwiga Bienkowska
Prashant Mali (CM4AI)University of California San Diego
Trey Ideker (CM4AI)University of California San Diego
Trey Ideker (CM4AI)University of California San Diego
Trey Ideker (CM4AI)University of California San Diego
Trey Ideker (CM4AI)University of California San Diego
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