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Paper Details

CRISPR-Cas9 epigenome editing enables high-throughput screening for functional regulatory elements in the human genome.
Nat Biotechnol
270
2017
-globin, -globin and HER2 loci, CERES, CRISPR, Cas9, DNase I, DNase I hypersensitive sites, HER2 loci, cell type, dCas9KRAB, dCas9KRAB repressor and dCas9p300 activator constructs, dCas9p300 activator, epigenomic regulatory element, functional regulatory elements, human, human cells, human genome, lentiviral single guide RNA, non-protein-coding elements, putative regulatory elements, regulatory element, regulatory elements
Author NameAffiliation
Alexias SafiCenter for Genomic and Computational Biology, Duke University
Lingyun SongCenter for Genomic and Computational Biology, Duke University
Gregory E CrawfordCenter for Genomic and Computational Biology, Duke University
Gregory E CrawfordDuke University Medical Center
Gregory E CrawfordCenter for Genomic and Computational Biology, Duke University
Gregory E CrawfordDuke University Medical Center
Timothy E ReddyDuke University
Timothy E ReddyCenter for Genomic and Computational Biology, Duke University
Timothy E ReddyDuke University Medical Center
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