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Paper Details

A genetic mouse model with postnatal <i>Nf1</i> and <i>p53</i> loss recapitulates the histology and transcriptome of human malignant peripheral nerve sheath tumor.
Neurooncol Adv
6
2021
CDKN2A, CDKN2A/B, CreER, GEM-MPNST, H3K27me3, Hippo, LATS1/2, Lats, Lats-driven tumors, Lats1, Lats2, MPNST, Malignant peripheral nerve sheath tumors, NF1, NP-Plp, NPcis) model, Nf1, PRC2, Plp, Plp-CreER allele, Trp53, genetically modified alleles, germline Nf1, human, malignant peripheral nerve sheath tumor, mice, mouse, nerve sheath tumors, p53, sarcomas, tumor, tumors
Author NameAffiliation
Brian L GudenasSt. Jude Children's Research Hospital
Paul A NorthcottSt. Jude Children's Research Hospital
Paul A NorthcottSt. Jude Children's Research Hospital
Angela C HirbeWashington University
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