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Paper Details

Hypoxia promotes stem cell phenotypes and poor prognosis through epigenetic regulation of DICER.
Nat Commun
176
2014
DICER, DICER promoter, KDM6A/B, MicroRNAs, ZEB1, breast cancer, cancer, human, human mammary epithelial cells, malignancies, miR-, miR-200, miRNA, microRNA, oxygen, oxygen-dependent H3K27me3 demethylases, patients, small regulatory RNAs, stem, stem cell, stem cell phenotypes, tumour, tumour stem cell
Breast Neoplasms, Cell Hypoxia, DEAD-box RNA Helicases, Epigenesis, Genetic, Epithelial-Mesenchymal Transition, Female, Gene Expression Regulation, Neoplastic, Gene Silencing, Humans, Neoplastic Stem Cells, Phenotype, Prognosis, Promoter Regions, Genetic, RNA Processing, Post-Transcriptional, Ribonuclease III
Author NameAffiliation
Jeroen J J P van den BeuckenPrincess Margaret Cancer Centre and Campbell Family Institute for Cancer Research, University Health Network
Jeroen J J P van den BeuckenMaastricht University Medical Center
Jeroen J J P van den BeuckenMaastricht University Medical Center
Elizabeth KochPrincess Margaret Cancer Centre and Campbell Family Institute for Cancer Research, University Health Network
Elizabeth KochUniversity of Toronto
Kenneth C ChuOntario Institute for Cancer Research
Rajesha RupaimooleThe University of Texas M.D. Anderson Cancer Center
Peggy PrickaertsMaastricht University Medical Center
Michiel E AdriaensHeart Failure Research Centre, Academic Medical Center
Michiel E AdriaensMaastricht University
Jan Willem VonckenMaastricht University Medical Center
Adrian L HarrisThe Weatherall Institute of Molecular Medicine, John Radcliffe Hospital
Francesca M BuffaThe Weatherall Institute of Molecular Medicine, John Radcliffe Hospital
Syed HaiderOntario Institute for Cancer Research
Maud H W StarmansMaastricht University Medical Center
Maud H W StarmansOntario Institute for Cancer Research
Cindy Q YaoUniversity of Toronto
Cindy Q YaoOntario Institute for Cancer Research
Mircea IvanThe Indiana University Melvin and Bren Simon Cancer Center
Cristina IvanCenter for RNA Interference and Non-Coding RNAs. The University of Texas M.D. Anderson Cancer Center
Chad V PecotThe University of Texas M.D. Anderson Cancer Center
Paul C BoutrosUniversity of Toronto
Paul C BoutrosOntario Institute for Cancer Research
Paul C BoutrosUniversity of Toronto
Anil K SoodThe University of Texas M.D. Anderson Cancer Center
Anil K SoodCenter for RNA Interference and Non-Coding RNAs. The University of Texas M.D. Anderson Cancer Center
Marianne KoritzinskyPrincess Margaret Cancer Centre and Campbell Family Institute for Cancer Research, University Health Network
Marianne KoritzinskyInstitute of Medical Science, University of Toronto
Marianne KoritzinskyUniversity of Toronto
Bradly G WoutersPrincess Margaret Cancer Centre and Campbell Family Institute for Cancer Research, University Health Network
Bradly G WoutersMaastricht University Medical Center
Bradly G WoutersUniversity of Toronto
Bradly G WoutersUniversity of Toronto
Bradly G WoutersOntario Institute for Cancer Research
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