Skip to Main Content

Paper Details

Gilteritinib or Chemotherapy for Relapsed or Refractory <i>FLT3</i>-Mutated AML.
N Engl J Med
707
2019
AML, FLT3, FLT3-Mutated AML, FLT3-mutated AML, FMS-like tyrosine kinase 3 gene, Gilteritinib, Patients, acute myeloid leukemia, anemia, febrile neutropenia, gilteritinib, patients, thrombocytopenia
Author NameAffiliation
Jorge CortesFrom the Abramson Cancer Center, University of Pennsylvania (A.E.P.), and Thomas Jefferson University (M.K.) - both in Philadelphia Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori, Istituto Di Ricovero e Cura a Carattere Scientifico (IRCCS), L. and A. Seragnoli Institute of Hematology, Bologna University Medical School, Ospedali Riuniti Villa Sofia-Cervello, and IRCCS San Raffaele Scientific Institute, Milan (F.C.) - all in Italy University of Texas M.D. Anderson Cancer Center, Houston (J.E.C.) Universitatsklinikum Giessen und Marburg, Germany (A.N.) Memorial Sloan Kettering Cancer Center, New York (E. Berman) Hospital Universitari i Politecnic La Fe, Instituto Carlos III, Madrid - both in Spain (P.M.) University of Maryland Greenebaum Comprehensive Cancer Center (M.R.B.) and Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University (M.J.L.) - both in Baltimore University of Chicago, and Astellas Pharma, E. Bahceci) - both in Illinois University of Minnesota, Minneapolis (C.U.) University of Alabama at Birmingham, A.D.S.) Hollings Cancer Center, Medical University of South Carolina, Charleston (R.S.) University of California, San Francisco (R.O.) National Taiwan University, Taiwan (W.-C.C.) Yale University School of Medicine, CT (N.P.) Centre Hospitalier Universitaire de Toulouse, Institut Universitaire du Cancer de Toulouse Oncopole, Universite Toulouse III Paul Sabatier, France (C.R.) Sendai Medical Center, National Hospital Organization, and University of Fukui, Fukui (N. Hosono) - both in Japan Seoul National University (S.-S.Y.) and Asan Medical Center, University of Ulsan College of Medicine (J.-H.L.) - both in Seoul, South Korea Wake Forest Baptist Medical Center, NC (T.P.) and Massachusetts General Hospital, Harvard Medical School
Timothy S PardeeFrom the Abramson Cancer Center, University of Pennsylvania (A.E.P.), and Thomas Jefferson University (M.K.) - both in Philadelphia Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori, Istituto Di Ricovero e Cura a Carattere Scientifico (IRCCS), L. and A. Seragnoli Institute of Hematology, Bologna University Medical School, Ospedali Riuniti Villa Sofia-Cervello, and IRCCS San Raffaele Scientific Institute, Milan (F.C.) - all in Italy University of Texas M.D. Anderson Cancer Center, Houston (J.E.C.) Universitatsklinikum Giessen und Marburg, Germany (A.N.) Memorial Sloan Kettering Cancer Center, New York (E. Berman) Hospital Universitari i Politecnic La Fe, Instituto Carlos III, Madrid - both in Spain (P.M.) University of Maryland Greenebaum Comprehensive Cancer Center (M.R.B.) and Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University (M.J.L.) - both in Baltimore University of Chicago, and Astellas Pharma, E. Bahceci) - both in Illinois University of Minnesota, Minneapolis (C.U.) University of Alabama at Birmingham, A.D.S.) Hollings Cancer Center, Medical University of South Carolina, Charleston (R.S.) University of California, San Francisco (R.O.) National Taiwan University, Taiwan (W.-C.C.) Yale University School of Medicine, CT (N.P.) Centre Hospitalier Universitaire de Toulouse, Institut Universitaire du Cancer de Toulouse Oncopole, Universite Toulouse III Paul Sabatier, France (C.R.) Sendai Medical Center, National Hospital Organization, and University of Fukui, Fukui (N. Hosono) - both in Japan Seoul National University (S.-S.Y.) and Asan Medical Center, University of Ulsan College of Medicine (J.-H.L.) - both in Seoul, South Korea Wake Forest Baptist Medical Center, NC (T.P.) and Massachusetts General Hospital, Harvard Medical School
Mark J LevisFrom the Abramson Cancer Center, University of Pennsylvania (A.E.P.), and Thomas Jefferson University (M.K.) - both in Philadelphia Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori, Istituto Di Ricovero e Cura a Carattere Scientifico (IRCCS), L. and A. Seragnoli Institute of Hematology, Bologna University Medical School, Ospedali Riuniti Villa Sofia-Cervello, and IRCCS San Raffaele Scientific Institute, Milan (F.C.) - all in Italy University of Texas M.D. Anderson Cancer Center, Houston (J.E.C.) Universitatsklinikum Giessen und Marburg, Germany (A.N.) Memorial Sloan Kettering Cancer Center, New York (E. Berman) Hospital Universitari i Politecnic La Fe, Instituto Carlos III, Madrid - both in Spain (P.M.) University of Maryland Greenebaum Comprehensive Cancer Center (M.R.B.) and Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University (M.J.L.) - both in Baltimore University of Chicago, and Astellas Pharma, E. Bahceci) - both in Illinois University of Minnesota, Minneapolis (C.U.) University of Alabama at Birmingham, A.D.S.) Hollings Cancer Center, Medical University of South Carolina, Charleston (R.S.) University of California, San Francisco (R.O.) National Taiwan University, Taiwan (W.-C.C.) Yale University School of Medicine, CT (N.P.) Centre Hospitalier Universitaire de Toulouse, Institut Universitaire du Cancer de Toulouse Oncopole, Universite Toulouse III Paul Sabatier, France (C.R.) Sendai Medical Center, National Hospital Organization, and University of Fukui, Fukui (N. Hosono) - both in Japan Seoul National University (S.-S.Y.) and Asan Medical Center, University of Ulsan College of Medicine (J.-H.L.) - both in Seoul, South Korea Wake Forest Baptist Medical Center, NC (T.P.) and Massachusetts General Hospital, Harvard Medical School
Mark J LevisFrom the Abramson Cancer Center, University of Pennsylvania (A.E.P.), and Thomas Jefferson University (M.K.) - both in Philadelphia Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori, Istituto Di Ricovero e Cura a Carattere Scientifico (IRCCS), L. and A. Seragnoli Institute of Hematology, Bologna University Medical School, Ospedali Riuniti Villa Sofia-Cervello, and IRCCS San Raffaele Scientific Institute, Milan (F.C.) - all in Italy University of Texas M.D. Anderson Cancer Center, Houston (J.E.C.) Universitatsklinikum Giessen und Marburg, Germany (A.N.) Memorial Sloan Kettering Cancer Center, New York (E. Berman) Hospital Universitari i Politecnic La Fe, Instituto Carlos III, Madrid - both in Spain (P.M.) University of Maryland Greenebaum Comprehensive Cancer Center (M.R.B.) and Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University (M.J.L.) - both in Baltimore University of Chicago, and Astellas Pharma, E. Bahceci) - both in Illinois University of Minnesota, Minneapolis (C.U.) University of Alabama at Birmingham, A.D.S.) Hollings Cancer Center, Medical University of South Carolina, Charleston (R.S.) University of California, San Francisco (R.O.) National Taiwan University, Taiwan (W.-C.C.) Yale University School of Medicine, CT (N.P.) Centre Hospitalier Universitaire de Toulouse, Institut Universitaire du Cancer de Toulouse Oncopole, Universite Toulouse III Paul Sabatier, France (C.R.) Sendai Medical Center, National Hospital Organization, and University of Fukui, Fukui (N. Hosono) - both in Japan Seoul National University (S.-S.Y.) and Asan Medical Center, University of Ulsan College of Medicine (J.-H.L.) - both in Seoul, South Korea Wake Forest Baptist Medical Center, NC (T.P.) and Massachusetts General Hospital, Harvard Medical School
  • 1 - 4

Datasets

ClinicalTrials.govClinicalTrials.gov, a registry and results database of of privately and publicly funded clinical studies conducted around the world, is operated by the U.S. National Library of Medicine (NLM). Structured study information is provided, voluntarily or to meet legal and policy requirements, by the sponsor or investigator responsible for the research. NLM does not verify the scientific validity or relevance of the submitted information beyond a limited quality control review for apparent errors, deficiencies, or inconsistencies.Link
ClinicalTrials.govClinicalTrials.gov, a registry and results database of of privately and publicly funded clinical studies conducted around the world, is operated by the U.S. National Library of Medicine (NLM). Structured study information is provided, voluntarily or to meet legal and policy requirements, by the sponsor or investigator responsible for the research. NLM does not verify the scientific validity or relevance of the submitted information beyond a limited quality control review for apparent errors, deficiencies, or inconsistencies.Link
ClinicalTrials.govClinicalTrials.gov, a registry and results database of of privately and publicly funded clinical studies conducted around the world, is operated by the U.S. National Library of Medicine (NLM). Structured study information is provided, voluntarily or to meet legal and policy requirements, by the sponsor or investigator responsible for the research. NLM does not verify the scientific validity or relevance of the submitted information beyond a limited quality control review for apparent errors, deficiencies, or inconsistencies.Link
ClinicalTrials.govClinicalTrials.gov, a registry and results database of of privately and publicly funded clinical studies conducted around the world, is operated by the U.S. National Library of Medicine (NLM). Structured study information is provided, voluntarily or to meet legal and policy requirements, by the sponsor or investigator responsible for the research. NLM does not verify the scientific validity or relevance of the submitted information beyond a limited quality control review for apparent errors, deficiencies, or inconsistencies.Link
ClinicalTrials.govClinicalTrials.gov, a registry and results database of of privately and publicly funded clinical studies conducted around the world, is operated by the U.S. National Library of Medicine (NLM). Structured study information is provided, voluntarily or to meet legal and policy requirements, by the sponsor or investigator responsible for the research. NLM does not verify the scientific validity or relevance of the submitted information beyond a limited quality control review for apparent errors, deficiencies, or inconsistencies.Link
ClinicalTrials.govClinicalTrials.gov, a registry and results database of of privately and publicly funded clinical studies conducted around the world, is operated by the U.S. National Library of Medicine (NLM). Structured study information is provided, voluntarily or to meet legal and policy requirements, by the sponsor or investigator responsible for the research. NLM does not verify the scientific validity or relevance of the submitted information beyond a limited quality control review for apparent errors, deficiencies, or inconsistencies.Link
ClinicalTrials.govClinicalTrials.gov, a registry and results database of of privately and publicly funded clinical studies conducted around the world, is operated by the U.S. National Library of Medicine (NLM). Structured study information is provided, voluntarily or to meet legal and policy requirements, by the sponsor or investigator responsible for the research. NLM does not verify the scientific validity or relevance of the submitted information beyond a limited quality control review for apparent errors, deficiencies, or inconsistencies.Link
ClinicalTrials.govClinicalTrials.gov, a registry and results database of of privately and publicly funded clinical studies conducted around the world, is operated by the U.S. National Library of Medicine (NLM). Structured study information is provided, voluntarily or to meet legal and policy requirements, by the sponsor or investigator responsible for the research. NLM does not verify the scientific validity or relevance of the submitted information beyond a limited quality control review for apparent errors, deficiencies, or inconsistencies.Link
ClinicalTrials.govClinicalTrials.gov, a registry and results database of of privately and publicly funded clinical studies conducted around the world, is operated by the U.S. National Library of Medicine (NLM). Structured study information is provided, voluntarily or to meet legal and policy requirements, by the sponsor or investigator responsible for the research. NLM does not verify the scientific validity or relevance of the submitted information beyond a limited quality control review for apparent errors, deficiencies, or inconsistencies.Link
ClinicalTrials.govClinicalTrials.gov, a registry and results database of of privately and publicly funded clinical studies conducted around the world, is operated by the U.S. National Library of Medicine (NLM). Structured study information is provided, voluntarily or to meet legal and policy requirements, by the sponsor or investigator responsible for the research. NLM does not verify the scientific validity or relevance of the submitted information beyond a limited quality control review for apparent errors, deficiencies, or inconsistencies.Link
ClinicalTrials.govClinicalTrials.gov, a registry and results database of of privately and publicly funded clinical studies conducted around the world, is operated by the U.S. National Library of Medicine (NLM). Structured study information is provided, voluntarily or to meet legal and policy requirements, by the sponsor or investigator responsible for the research. NLM does not verify the scientific validity or relevance of the submitted information beyond a limited quality control review for apparent errors, deficiencies, or inconsistencies.Link
ClinicalTrials.govClinicalTrials.gov, a registry and results database of of privately and publicly funded clinical studies conducted around the world, is operated by the U.S. National Library of Medicine (NLM). Structured study information is provided, voluntarily or to meet legal and policy requirements, by the sponsor or investigator responsible for the research. NLM does not verify the scientific validity or relevance of the submitted information beyond a limited quality control review for apparent errors, deficiencies, or inconsistencies.Link
ClinicalTrials.govClinicalTrials.gov, a registry and results database of of privately and publicly funded clinical studies conducted around the world, is operated by the U.S. National Library of Medicine (NLM). Structured study information is provided, voluntarily or to meet legal and policy requirements, by the sponsor or investigator responsible for the research. NLM does not verify the scientific validity or relevance of the submitted information beyond a limited quality control review for apparent errors, deficiencies, or inconsistencies.Link
ClinicalTrials.govClinicalTrials.gov, a registry and results database of of privately and publicly funded clinical studies conducted around the world, is operated by the U.S. National Library of Medicine (NLM). Structured study information is provided, voluntarily or to meet legal and policy requirements, by the sponsor or investigator responsible for the research. NLM does not verify the scientific validity or relevance of the submitted information beyond a limited quality control review for apparent errors, deficiencies, or inconsistencies.Link
ClinicalTrials.govClinicalTrials.gov, a registry and results database of of privately and publicly funded clinical studies conducted around the world, is operated by the U.S. National Library of Medicine (NLM). Structured study information is provided, voluntarily or to meet legal and policy requirements, by the sponsor or investigator responsible for the research. NLM does not verify the scientific validity or relevance of the submitted information beyond a limited quality control review for apparent errors, deficiencies, or inconsistencies.Link