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Paper Details

CRD-733, a Novel PDE9 (Phosphodiesterase 9) Inhibitor, Reverses Pressure Overload-Induced Heart Failure.
Circulation: Heart Failure
14
2021
-C, CRD-, CRD-733, HF, LV dysfunction, LV hypertrophy, Mice, NP (natriuretic peptide) receptor, PDE9, Phosphodiesterase 9, Pressure Overload-Induced Heart Failure, Ser273, cGMP, cGMP-dependent protein kinase I, cardiac myosin binding protein, cyclic guanosine monophosphate, heart failure, human, hypertrophic heart disease, left atrial dilation, left ventricular (LV) hypertrophy, mice, mouse, phosphodiesterase 9, phosphorylation site, pulmonary edema, transverse aortic constriction
Author NameAffiliation
Richard H KarasMolecular Cardiology Research Institute, Tufts Medical Center
Michael E MendelsohnCardurion Pharmaceuticals
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Datasets

Release 1.2