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Paper Details

Downregulation of TREM-like transcript-1 and collagen receptor α2 subunit, two novel RUNX1-targets, contributes to platelet dysfunction in familial platelet disorder with predisposition to acute myelogenous leukemia.
Haematologica
15
2019
AML, Down-regulated genes, H3K27Ac, ITGA2, MK, RUNX1, RUNX1 sites, TLT-1, TLT-1 deficiency, TREM-like transcript (TLT)-1, TREM-like transcript-1, TREML1, acute myelogenous leukemia, anti-TLT-1 antibody, collagen, collagen receptor 2 subunit, collagen receptor 2-beta ()-1, familial platelet disorder, fibrinogen, genes, integrin subunit, integrin subunit alpha ()-2, mCherry reporter, megakaryocytes, patient, patient platelets, patients, platelet, platelet dysfunction, platelet phenotype, platelets, promoters, recombinant soluble TLT-1, shRUNX1-transduced megakaryocytes, thrombocytopenia
Author NameAffiliation
Anna RaimbaultINSERM UMR 0, Universite Paris-Saclay
Rémi FavierINSERM UMR 0, Universite Paris-Saclay
Rémi FavierAssistance Publique-Hopitaux de Paris
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