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Paper Details

Functional epigenetics approach identifies BRM/SMARCA2 as a critical synthetic lethal target in BRG1-deficient cancers.
Proc Natl Acad Sci U S A
264
2014
BRG1, BRG1 mutated cancers, BRG1-deficient cancer, BRG1-deficient cancer cells, BRG1-deficient cancers, BRG1-mutant tumors, BRM, DNA-dependent ATPase, H3K9me3, SMARCA2, SMARCA4, SNF, SWI, cancer, cancer cell lines, cancers, chromatin, epigenome, lung adenocarcinomas, mSWI, synthetic lethality, tumor, tumor cells

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