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Paper Details

A Whole-Genome CRISPR Screen Identifies AHR Loss as a Mechanism of Resistance to a PARP7 Inhibitor.
Mol Cancer Ther
6
2022
AHR, BRCA1, BRCA1 and BRCA2-related cancers, BRCA2, PARP family, PARP1, PARP2, PARP7, RBN-2397, cancer, cohesin complex, human, polycyclic aromatic hydrocarbon, polycyclic aromatic hydrocarbon receptor AHR
Clustered Regularly Interspaced Short Palindromic Repeats, Genome, Humans, Neoplasms, Poly(ADP-ribose) Polymerase Inhibitors
Author NameAffiliation
Huadong ChenHelen Diller Family Comprehensive Cancer Center, University of California san francisco
Morgan E DiolaitiHelen Diller Family Comprehensive Cancer Center, University of California san francisco
Morgan E Diolaiti
Patrick C O'LearyHelen Diller Family Comprehensive Cancer Center, University of California san francisco
Patrick C O'Leary
Ajda Rojc
Ajda RojcUniversity of California san francisco
Ajda RojcThe J. David Gladstone Institute of Data Science and Biotechnology
Ajda RojcQuantitative Biosciences Institute, University of California san francisco
Nevan J Krogan (CM4AI)
Nevan J Krogan (CM4AI)University of California san francisco
Nevan J Krogan (CM4AI)The J. David Gladstone Institute of Data Science and Biotechnology
Nevan J Krogan (CM4AI)Quantitative Biosciences Institute, University of California san francisco
Minkyu Kim
Minkyu KimUniversity of California san francisco
Minkyu KimThe J. David Gladstone Institute of Data Science and Biotechnology
Minkyu KimQuantitative Biosciences Institute, University of California san francisco
Alan AshworthHelen Diller Family Comprehensive Cancer Center, University of California san francisco
Alan Ashworth
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