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Paper Details

Constitutively active Lyn kinase causes a cutaneous small vessel vasculitis and liver fibrosis syndrome.
Nat Commun
5
2023
2-integrins, ICAM-1, LYN, Lyn kinase, Neutrophilic inflammation, Q507, Src kinase, Src-family tyrosine kinase, TNF, Y508, boys, cutaneous small vessel vasculitis, damaging, damaging immune cells, dasatinib, hepatic fibrosis, iECs, liver fibrosis, liver fibrosis syndrome, monogenic autoinflammatory diseases, neutrophil, neutrophilic cutaneous small vessel vasculitis, patient, patient neutrophils, patient-derived endothelial cells, patients, systemic inflammation, tyrosine
Author NameAffiliation
Guibin Chenand Blood Institute, National Institutes of Health
Stephen M HewittNational Cancer Institute, National Institutes of Health
Stephen M HewittNational Cancer Institute, National Institutes of Health
Stefania PittalugaNational Cancer Institute, National Institutes of Health
Stefania PittalugaNational Cancer Institute, National Institutes of Health
Sergio D RosenzweigClinical Center, National Institutes of Health
Douglas B KuhnsCollaborative Clinical Research Branch/Neutrophil Monitoring Laboratory, National Institute of Allergy and Infectious Diseases, National Institutes of Health
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