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Paper Details

Comparative analysis of TCR and CAR signaling informs CAR designs with superior antigen sensitivity and in vivo function.
Sci Signal
63
2021
4-1BB, 4-1BB/CD3 CAR sequence, CAR, CAR T cell, CARs, CD3, Chimeric antigen receptor, GRB2 domains, LAT, T cell, T cell receptor, TCR, TCRs, breast cancer, hematological malignancies, human, leukemia, leukemias, lymphoma, lymphomas, multiple myeloma, patients, primary human T cells, solid tumors, tumor, tumor cells
Author NameAffiliation
Jacob J KennedyClinical Research Division, Fred Hutchinson Cancer Research Center
Jeffrey R WhiteakerClinical Research Division, Fred Hutchinson Cancer Research Center
Raphael GottardoFred Hutchinson Cancer Research Center
Raphael GottardoFred Hutchinson Cancer Research Center
Amanda G PaulovichClinical Research Division, Fred Hutchinson Cancer Research Center
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Release 1.2