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Incorporation of a bioactive reverse-turn heterocycle into a peptide template using solid-phase synthesis to probe melanocortin receptor selectivity and ligand conformations by 2D 1H NMR.
J Med Chem
13
2011
(1)H, -, 1H, AGRP, G-protein-coupled receptors, GPCRs, His-Phe-Arg-Trp, MC1R, MC5R, cyclic, melanocortin, melanocortin receptor, melanocortin receptor isoforms, reverse

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