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Paper Details

A novel dominant-negative mutation in Gdf5 generated by ENU mutagenesis impairs joint formation and causes osteoarthritis in mice.
Hum Mol Genet
52
2007
ENU, GDF5, GDF5 mutations, GDF5 protein, Gdf5, Gdf5 allele, Growth and differentiation factor 5, N-ethyl-N-nitrosourea, OA, OA of the elbow joint, W408R, amino acid, ankylosis, ankylosis of the knee joint, brachypodism, human, human GDF5 mutations, mice, mouse, mutant GDF5 protein, osteoarthritis, shortening and joint ankylosis of the, wild-type GDF5 protein

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Release 1.2