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Paper Details

Mutation of the salt bridge-forming residues in the ETV6-SAM domain interface blocks ETV6-NTRK3-induced cellular transformation.
J Biol Chem
12
2013
Akt, Arg, Asp, C, C-terminal, EN, ETV6, ETV6-NTRK3 (EN) chimeric oncogene, Glu, Lys, MAPK, Mek1/2, N, NIH3T3 cells, NTRK3, PI3K, PTK, PTK domain, Ras, SAM, SAM domain, TEL, neurotrophin-3 receptor NTRK3, nude mice, protein-tyrosine kinase, sterile -motif, t(12;15) translocation, tumor, tyrosine

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