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Paper Details

Defective insulin receptor signaling in hPSCs skews pluripotency and negatively perturbs neural differentiation.
J Biol Chem
2
2021
ERK1/2, ERK2, FOXG1, Human, Human embryonic stem cells, IR, IRs, OCT4, PAX6, RNA, SOX1, cortical neuron, genes, hPSC, hPSC lines, hPSCs, human, human pluripotent stem cell, insulin receptor, luciferase, mature cell types, neural lineage, pAKT, pERK1/2, pluripotency gene, pluripotent stem cells, shRNAs, stem cell
Author NameAffiliation
Marina A GritsenkoPacific Northwest National Laboratory
Marina A GritsenkoPacific Northwest National Laboratory
John L RinnHarvard University, and Broad Institute of MIT
Richard D SmithPacific Northwest National Laboratory
Richard D SmithPacific Northwest National Laboratory
Wei-Jun QianPacific Northwest National Laboratory
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