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Paper Details

CoGAPS matrix factorization algorithm identifies transcriptional changes in AP-2alpha target genes in feedback from therapeutic inhibition of the EGFR network.
Oncotarget
9
2016
AP-2 family, AP-2 transcription factors, AP-2alpha, AP-2alpha gene expression signatures, AP-2alpha target genes, CDKN2A gene, Cancer, EGFR, EGFR gene, EGFR network, HNSCC, HNSCC cell lines, HNSCC tumors, HRAS, HaCaT cells, HaCaT keratinocyte cell line model, MAPK, MEK, PI3K, Patients, afatinib, cancer, cancer cells, cetuximab, gefitinib, gene, growth factor receptors, mTOR, oncogene, transcription factors, tumors
Author NameAffiliation
Elana J FertigSidney Kimmel Comprehensive Cancer Center, Johns Hopkins University
Jason D HowardSidney Kimmel Comprehensive Cancer Center, Johns Hopkins University
Jason D HowardSidney Kimmel Comprehensive Cancer Center, Johns Hopkins University
Siân Jones
Alexander V FavorovSidney Kimmel Comprehensive Cancer Center, Johns Hopkins University
Alexander V FavorovSidney Kimmel Comprehensive Cancer Center, Johns Hopkins University
Alexander V FavorovResearch Institute for Genetics and Selection of Industrial Microorganisms
Alexander V FavorovVavilov Institute of General Genetics
Alexander V FavorovVavilov Institute of General Genetics
Alexander V FavorovResearch Institute for Genetics and Selection of Industrial Microorganisms
Genevieve L Stein-O'BrienInstitute of Genetic Medicine, Johns Hopkins University
Genevieve L Stein-O'BrienLieber Institute for Brain Development
Daria A GaykalovaJohns Hopkins University School of Medicine
Michael F OchsThe College of New Jersey
Michael F OchsThe College of New Jersey
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