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Paper Details

Human JAK1 gain of function causes dysregulated myelopoeisis and severe allergic inflammation.
JCI Insight
3
2022
Human, IFN, IL-, IL-4, JAK1, JAK1/2, JAK1GOF, JAK1GOF (p., JAK1GOF variant, Primary atopic disorders, Th cell, allergic disease, allergic inflammation, atopic immune dysregulation, atopy, children, dysregulated genes, dysregulated myelopoeisis, eosinophilia, eosinophilic and allergic disease, human, human induced pluripotent stem cells, iPSCs, inborn errors of immunity, patients, polygenic allergic disease, ruxolitinib, zebrafish
Author NameAffiliation
Aabida SaferaliUniversity of British Columbia
Aabida SaferaliBrigham and Women's Hospital, Harvard Medical School
Aabida SaferaliBC Children's Hospital
Suzanne M Vercauteren
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Release 1.2