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Paper Details

Transcription factor competition at the γ-globin promoters controls hemoglobin switching.
Nat Genet
40
2021
-, -globin promoters, 50-kb -globin gene cluster, BCL11A, BCL11A-binding site, CRISPR, Cas9, HbA, HbF, KRAB, LCR, NF-Y, VP64, activator element, adult erythroid cells, adult hemoglobin, dCas9, fetal hemoglobin, globin, globin gene, hemoglobin, locus control region, proximal CCAAT box, the
Author NameAffiliation
Qian ZhuDana-Farber Cancer Institute and Harvard Medical School
Luca PinelloMolecular Pathology Unit & Center for Cancer Research, Massachusetts General Hospital, Harvard Medical School
Guo-Cheng YuanDana-Farber Cancer Institute and Harvard Medical School
Guo-Cheng YuanIcahn School of Medicine at Mount Sinai
Daniel E BauerDana-Farber Cancer Institute and Boston Children's Hospital, Harvard Medical School
Stuart H OrkinDana-Farber Cancer Institute and Boston Children's Hospital, Harvard Medical School
Stuart H OrkinHoward Hughes Medical Institute
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