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Paper Details

Novel gRNA design pipeline to develop broad-spectrum CRISPR/Cas9 gRNAs for safe targeting of the HIV-1 quasispecies in patients.
Sci Rep
22
2019
-, CRISPR, Cas9, Cas9 gRNAs, D, D-LTR, D-LTR-P4-227913, HIV, HIV-1, HIV-1-infected samples, LTRs, P4, P4R5 cells, TAR, TZM-bl or, gRNA, gRNAs, guide RNAs, patient, patient-derived sequences, patients, vQS
Author NameAffiliation
Will DampierDrexel University College of Medicine
Will DampierCenter for Molecular Virology and Translational Neuroscience, Institute for Molecular Medicine and Infectious Disease, Drexel University College of Medicine
Will DampierDrexel University
Garth D EhrlichDrexel University College of Medicine
Garth D EhrlichDrexel University College of Medicine
Garth D EhrlichSidney Kimmel Cancer Center, Thomas Jefferson University
Garth D EhrlichCenter for Advanced Microbial Processing, Institute for Molecular Medicine and Infectious Disease, Drexel University College of Medicine
Garth D EhrlichCenter for Genomic Sciences, Institute for Molecular Medicine and Infectious Disease, Drexel University College of Medicine
Garth D EhrlichCenter for Molecular Virology and Translational Neuroscience, Institute for Molecular Medicine and Infectious Disease, Drexel University College of Medicine
Zsofia SzepCenter for Clinical and Translational Medicine, Institute for Molecular Medicine and Infectious Disease
Zsofia SzepDrexel University College of Medicine
Jeffrey M JacobsonLewis Katz School of Medicine, Temple University
Jeffrey M JacobsonLewis Katz School of Medicine, Temple University
Jeffrey M JacobsonCenter for Translational AIDS Research, Lewis Katz School of Medicine, Temple University
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