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Paper Details

The DHODH inhibitor PTC299 arrests SARS-CoV-2 replication and suppresses induction of inflammatory cytokines.
Virus Research
49
2021
COVID-19, DHODH, Ebola virus, IL-17, IL-17 F, IL-17A, PTC299, SARS, SARS-, SARS-COV-2, SARS-COV-2 virus, SARS-CoV-, SARS-CoV-2, VEGF, coronavirus disease, dihydroorotate, dihydroorotate dehydrogenase, human, interleukin (IL)-6, pyrimidine nucleotide, tissue culture, tissue culture models, vascular endothelial growth factor
Author NameAffiliation
Jeremy LubanUniversity of Massachusetts Medical School, USA Broad Institute of Harvard and MIT
Rachel A SattlerUniversity of Texas Medical Branch at Galveston
Elke MühlbergerBoston University School of Medicine, Boston University
Jason D GraciInc. South Plainfield
Liangxian CaoInc. South Plainfield
Marla WeetallInc. South Plainfield
Christopher R TrottaInc. South Plainfield
Joseph M ColacinoInc. South Plainfield
Sina BavariUnited States Army Medical Research Institute of Infectious Diseases
Caterina Strambio-De-CastilliaUniversity of Massachusetts Medical School
Ellen L SuderBoston University School of Medicine, Boston University
Yetao WangUniversity of Massachusetts Medical School
Veronica SolovevaUnited States Army Medical Research Institute of Infectious Diseases
Katherine Cintron-LueInc. South Plainfield
Nikolai A NaryshkinInc. South Plainfield
Mark PykettInc. South Plainfield
Ellen M WelchInc. South Plainfield
Kylie O'KeefeInc. South Plainfield
Ronald KongInc. South Plainfield
Elizabeth GoodwinInc. South Plainfield
Allan JacobsonUniversity of Massachusetts Medical School
Slobodan PaesslerUniversity of Texas Medical Branch at Galveston
Stuart W PeltzInc. South Plainfield
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