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Paper Details

Sotagliflozin in Patients with Diabetes and Chronic Kidney Disease.
N Engl J Med
586
2021
Author NameAffiliation
Deepak L BhattFrom Brigham and Women's Hospital Heart and Vascular Center and Harvard Medical School, B.M.S.) Colorado Prevention Center Clinical Research and Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora (M.S.) the State University of New York Downstate School of Public Health, Brooklyn (M.S.) the University of Michigan, Ann Arbor (B.P.) Li Ka Shing Knowledge Institute and the Division of Endocrinology and Metabolism, St. Michael's Hospital, University of Toronto (L.A.L.), Women's College Hospital and Peter Munk Cardiac Centre (J.A.U.), University Health Network, University of Toronto - all in Toronto the University of Texas Southwestern Medical Center and Parkland Health and Hospital System, and Lexicon Pharmaceuticals, The Woodlands (P.L.) - both in Texas Vanderbilt University Medical Center, and Clinical Nutrition, Oregon Health and Science University, Yale School of Medicine, CT (S.E.I.) Saint Luke's Mid America Heart Institute, University of Missouri-Kansas City, Aston University, Imperial College London, Estudios Clinicos Latinoamerica, Instituto Cardiovascular de Rosario, Argentina (R.D.) Duke Clinical Research Institute, Duke University School of Medicine, NC (R.D.L.) and Universite de Paris, Assistance Publique-Hopitaux de Paris, INSERM Unite 8
Christopher P CannonFrom Brigham and Women's Hospital Heart and Vascular Center and Harvard Medical School, B.M.S.) Colorado Prevention Center Clinical Research and Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora (M.S.) the State University of New York Downstate School of Public Health, Brooklyn (M.S.) the University of Michigan, Ann Arbor (B.P.) Li Ka Shing Knowledge Institute and the Division of Endocrinology and Metabolism, St. Michael's Hospital, University of Toronto (L.A.L.), Women's College Hospital and Peter Munk Cardiac Centre (J.A.U.), University Health Network, University of Toronto - all in Toronto the University of Texas Southwestern Medical Center and Parkland Health and Hospital System, and Lexicon Pharmaceuticals, The Woodlands (P.L.) - both in Texas Vanderbilt University Medical Center, and Clinical Nutrition, Oregon Health and Science University, Yale School of Medicine, CT (S.E.I.) Saint Luke's Mid America Heart Institute, University of Missouri-Kansas City, Aston University, Imperial College London, Estudios Clinicos Latinoamerica, Instituto Cardiovascular de Rosario, Argentina (R.D.) Duke Clinical Research Institute, Duke University School of Medicine, NC (R.D.L.) and Universite de Paris, Assistance Publique-Hopitaux de Paris, INSERM Unite 8
Julia B LewisFrom Brigham and Women's Hospital Heart and Vascular Center and Harvard Medical School, B.M.S.) Colorado Prevention Center Clinical Research and Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora (M.S.) the State University of New York Downstate School of Public Health, Brooklyn (M.S.) the University of Michigan, Ann Arbor (B.P.) Li Ka Shing Knowledge Institute and the Division of Endocrinology and Metabolism, St. Michael's Hospital, University of Toronto (L.A.L.), Women's College Hospital and Peter Munk Cardiac Centre (J.A.U.), University Health Network, University of Toronto - all in Toronto the University of Texas Southwestern Medical Center and Parkland Health and Hospital System, and Lexicon Pharmaceuticals, The Woodlands (P.L.) - both in Texas Vanderbilt University Medical Center, and Clinical Nutrition, Oregon Health and Science University, Yale School of Medicine, CT (S.E.I.) Saint Luke's Mid America Heart Institute, University of Missouri-Kansas City, Aston University, Imperial College London, Estudios Clinicos Latinoamerica, Instituto Cardiovascular de Rosario, Argentina (R.D.) Duke Clinical Research Institute, Duke University School of Medicine, NC (R.D.L.) and Universite de Paris, Assistance Publique-Hopitaux de Paris, INSERM Unite 8
Mikhail KosiborodFrom Brigham and Women's Hospital Heart and Vascular Center and Harvard Medical School, B.M.S.) Colorado Prevention Center Clinical Research and Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora (M.S.) the State University of New York Downstate School of Public Health, Brooklyn (M.S.) the University of Michigan, Ann Arbor (B.P.) Li Ka Shing Knowledge Institute and the Division of Endocrinology and Metabolism, St. Michael's Hospital, University of Toronto (L.A.L.), Women's College Hospital and Peter Munk Cardiac Centre (J.A.U.), University Health Network, University of Toronto - all in Toronto the University of Texas Southwestern Medical Center and Parkland Health and Hospital System, and Lexicon Pharmaceuticals, The Woodlands (P.L.) - both in Texas Vanderbilt University Medical Center, and Clinical Nutrition, Oregon Health and Science University, Yale School of Medicine, CT (S.E.I.) Saint Luke's Mid America Heart Institute, University of Missouri-Kansas City, Aston University, Imperial College London, Estudios Clinicos Latinoamerica, Instituto Cardiovascular de Rosario, Argentina (R.D.) Duke Clinical Research Institute, Duke University School of Medicine, NC (R.D.L.) and Universite de Paris, Assistance Publique-Hopitaux de Paris, INSERM Unite 8
David Z I CherneyFrom Brigham and Women's Hospital Heart and Vascular Center and Harvard Medical School, B.M.S.) Colorado Prevention Center Clinical Research and Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora (M.S.) the State University of New York Downstate School of Public Health, Brooklyn (M.S.) the University of Michigan, Ann Arbor (B.P.) Li Ka Shing Knowledge Institute and the Division of Endocrinology and Metabolism, St. Michael's Hospital, University of Toronto (L.A.L.), Women's College Hospital and Peter Munk Cardiac Centre (J.A.U.), University Health Network, University of Toronto - all in Toronto the University of Texas Southwestern Medical Center and Parkland Health and Hospital System, and Lexicon Pharmaceuticals, The Woodlands (P.L.) - both in Texas Vanderbilt University Medical Center, and Clinical Nutrition, Oregon Health and Science University, Yale School of Medicine, CT (S.E.I.) Saint Luke's Mid America Heart Institute, University of Missouri-Kansas City, Aston University, Imperial College London, Estudios Clinicos Latinoamerica, Instituto Cardiovascular de Rosario, Argentina (R.D.) Duke Clinical Research Institute, Duke University School of Medicine, NC (R.D.L.) and Universite de Paris, Assistance Publique-Hopitaux de Paris, INSERM Unite 8
Jamie P DwyerFrom Brigham and Women's Hospital Heart and Vascular Center and Harvard Medical School, B.M.S.) Colorado Prevention Center Clinical Research and Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora (M.S.) the State University of New York Downstate School of Public Health, Brooklyn (M.S.) the University of Michigan, Ann Arbor (B.P.) Li Ka Shing Knowledge Institute and the Division of Endocrinology and Metabolism, St. Michael's Hospital, University of Toronto (L.A.L.), Women's College Hospital and Peter Munk Cardiac Centre (J.A.U.), University Health Network, University of Toronto - all in Toronto the University of Texas Southwestern Medical Center and Parkland Health and Hospital System, and Lexicon Pharmaceuticals, The Woodlands (P.L.) - both in Texas Vanderbilt University Medical Center, and Clinical Nutrition, Oregon Health and Science University, Yale School of Medicine, CT (S.E.I.) Saint Luke's Mid America Heart Institute, University of Missouri-Kansas City, Aston University, Imperial College London, Estudios Clinicos Latinoamerica, Instituto Cardiovascular de Rosario, Argentina (R.D.) Duke Clinical Research Institute, Duke University School of Medicine, NC (R.D.L.) and Universite de Paris, Assistance Publique-Hopitaux de Paris, INSERM Unite 8
Benjamin M SciricaFrom Brigham and Women's Hospital Heart and Vascular Center and Harvard Medical School, B.M.S.) Colorado Prevention Center Clinical Research and Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora (M.S.) the State University of New York Downstate School of Public Health, Brooklyn (M.S.) the University of Michigan, Ann Arbor (B.P.) Li Ka Shing Knowledge Institute and the Division of Endocrinology and Metabolism, St. Michael's Hospital, University of Toronto (L.A.L.), Women's College Hospital and Peter Munk Cardiac Centre (J.A.U.), University Health Network, University of Toronto - all in Toronto the University of Texas Southwestern Medical Center and Parkland Health and Hospital System, and Lexicon Pharmaceuticals, The Woodlands (P.L.) - both in Texas Vanderbilt University Medical Center, and Clinical Nutrition, Oregon Health and Science University, Yale School of Medicine, CT (S.E.I.) Saint Luke's Mid America Heart Institute, University of Missouri-Kansas City, Aston University, Imperial College London, Estudios Clinicos Latinoamerica, Instituto Cardiovascular de Rosario, Argentina (R.D.) Duke Clinical Research Institute, Duke University School of Medicine, NC (R.D.L.) and Universite de Paris, Assistance Publique-Hopitaux de Paris, INSERM Unite 8
Renato D LopesFrom Brigham and Women's Hospital Heart and Vascular Center and Harvard Medical School, B.M.S.) Colorado Prevention Center Clinical Research and Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora (M.S.) the State University of New York Downstate School of Public Health, Brooklyn (M.S.) the University of Michigan, Ann Arbor (B.P.) Li Ka Shing Knowledge Institute and the Division of Endocrinology and Metabolism, St. Michael's Hospital, University of Toronto (L.A.L.), Women's College Hospital and Peter Munk Cardiac Centre (J.A.U.), University Health Network, University of Toronto - all in Toronto the University of Texas Southwestern Medical Center and Parkland Health and Hospital System, and Lexicon Pharmaceuticals, The Woodlands (P.L.) - both in Texas Vanderbilt University Medical Center, and Clinical Nutrition, Oregon Health and Science University, Yale School of Medicine, CT (S.E.I.) Saint Luke's Mid America Heart Institute, University of Missouri-Kansas City, Aston University, Imperial College London, Estudios Clinicos Latinoamerica, Instituto Cardiovascular de Rosario, Argentina (R.D.) Duke Clinical Research Institute, Duke University School of Medicine, NC (R.D.L.) and Universite de Paris, Assistance Publique-Hopitaux de Paris, INSERM Unite 8
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Datasets

ClinicalTrials.govClinicalTrials.gov, a registry and results database of of privately and publicly funded clinical studies conducted around the world, is operated by the U.S. National Library of Medicine (NLM). Structured study information is provided, voluntarily or to meet legal and policy requirements, by the sponsor or investigator responsible for the research. NLM does not verify the scientific validity or relevance of the submitted information beyond a limited quality control review for apparent errors, deficiencies, or inconsistencies.Link
ClinicalTrials.govClinicalTrials.gov, a registry and results database of of privately and publicly funded clinical studies conducted around the world, is operated by the U.S. National Library of Medicine (NLM). Structured study information is provided, voluntarily or to meet legal and policy requirements, by the sponsor or investigator responsible for the research. NLM does not verify the scientific validity or relevance of the submitted information beyond a limited quality control review for apparent errors, deficiencies, or inconsistencies.Link
ClinicalTrials.govClinicalTrials.gov, a registry and results database of of privately and publicly funded clinical studies conducted around the world, is operated by the U.S. National Library of Medicine (NLM). Structured study information is provided, voluntarily or to meet legal and policy requirements, by the sponsor or investigator responsible for the research. NLM does not verify the scientific validity or relevance of the submitted information beyond a limited quality control review for apparent errors, deficiencies, or inconsistencies.Link
ClinicalTrials.govClinicalTrials.gov, a registry and results database of of privately and publicly funded clinical studies conducted around the world, is operated by the U.S. National Library of Medicine (NLM). Structured study information is provided, voluntarily or to meet legal and policy requirements, by the sponsor or investigator responsible for the research. NLM does not verify the scientific validity or relevance of the submitted information beyond a limited quality control review for apparent errors, deficiencies, or inconsistencies.Link
ClinicalTrials.govClinicalTrials.gov, a registry and results database of of privately and publicly funded clinical studies conducted around the world, is operated by the U.S. National Library of Medicine (NLM). Structured study information is provided, voluntarily or to meet legal and policy requirements, by the sponsor or investigator responsible for the research. NLM does not verify the scientific validity or relevance of the submitted information beyond a limited quality control review for apparent errors, deficiencies, or inconsistencies.Link
ClinicalTrials.govClinicalTrials.gov, a registry and results database of of privately and publicly funded clinical studies conducted around the world, is operated by the U.S. National Library of Medicine (NLM). Structured study information is provided, voluntarily or to meet legal and policy requirements, by the sponsor or investigator responsible for the research. NLM does not verify the scientific validity or relevance of the submitted information beyond a limited quality control review for apparent errors, deficiencies, or inconsistencies.Link
ClinicalTrials.govClinicalTrials.gov, a registry and results database of of privately and publicly funded clinical studies conducted around the world, is operated by the U.S. National Library of Medicine (NLM). Structured study information is provided, voluntarily or to meet legal and policy requirements, by the sponsor or investigator responsible for the research. NLM does not verify the scientific validity or relevance of the submitted information beyond a limited quality control review for apparent errors, deficiencies, or inconsistencies.Link
ClinicalTrials.govClinicalTrials.gov, a registry and results database of of privately and publicly funded clinical studies conducted around the world, is operated by the U.S. National Library of Medicine (NLM). Structured study information is provided, voluntarily or to meet legal and policy requirements, by the sponsor or investigator responsible for the research. NLM does not verify the scientific validity or relevance of the submitted information beyond a limited quality control review for apparent errors, deficiencies, or inconsistencies.Link
ClinicalTrials.govClinicalTrials.gov, a registry and results database of of privately and publicly funded clinical studies conducted around the world, is operated by the U.S. National Library of Medicine (NLM). Structured study information is provided, voluntarily or to meet legal and policy requirements, by the sponsor or investigator responsible for the research. NLM does not verify the scientific validity or relevance of the submitted information beyond a limited quality control review for apparent errors, deficiencies, or inconsistencies.Link
ClinicalTrials.govClinicalTrials.gov, a registry and results database of of privately and publicly funded clinical studies conducted around the world, is operated by the U.S. National Library of Medicine (NLM). Structured study information is provided, voluntarily or to meet legal and policy requirements, by the sponsor or investigator responsible for the research. NLM does not verify the scientific validity or relevance of the submitted information beyond a limited quality control review for apparent errors, deficiencies, or inconsistencies.Link
ClinicalTrials.govClinicalTrials.gov, a registry and results database of of privately and publicly funded clinical studies conducted around the world, is operated by the U.S. National Library of Medicine (NLM). Structured study information is provided, voluntarily or to meet legal and policy requirements, by the sponsor or investigator responsible for the research. NLM does not verify the scientific validity or relevance of the submitted information beyond a limited quality control review for apparent errors, deficiencies, or inconsistencies.Link
ClinicalTrials.govClinicalTrials.gov, a registry and results database of of privately and publicly funded clinical studies conducted around the world, is operated by the U.S. National Library of Medicine (NLM). Structured study information is provided, voluntarily or to meet legal and policy requirements, by the sponsor or investigator responsible for the research. NLM does not verify the scientific validity or relevance of the submitted information beyond a limited quality control review for apparent errors, deficiencies, or inconsistencies.Link
ClinicalTrials.govClinicalTrials.gov, a registry and results database of of privately and publicly funded clinical studies conducted around the world, is operated by the U.S. National Library of Medicine (NLM). Structured study information is provided, voluntarily or to meet legal and policy requirements, by the sponsor or investigator responsible for the research. NLM does not verify the scientific validity or relevance of the submitted information beyond a limited quality control review for apparent errors, deficiencies, or inconsistencies.Link
ClinicalTrials.govClinicalTrials.gov, a registry and results database of of privately and publicly funded clinical studies conducted around the world, is operated by the U.S. National Library of Medicine (NLM). Structured study information is provided, voluntarily or to meet legal and policy requirements, by the sponsor or investigator responsible for the research. NLM does not verify the scientific validity or relevance of the submitted information beyond a limited quality control review for apparent errors, deficiencies, or inconsistencies.Link
ClinicalTrials.govClinicalTrials.gov, a registry and results database of of privately and publicly funded clinical studies conducted around the world, is operated by the U.S. National Library of Medicine (NLM). Structured study information is provided, voluntarily or to meet legal and policy requirements, by the sponsor or investigator responsible for the research. NLM does not verify the scientific validity or relevance of the submitted information beyond a limited quality control review for apparent errors, deficiencies, or inconsistencies.Link