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Paper Title
Metabolic Enzyme DLST Promotes Tumor Aggression and Reveals a Vulnerability to OXPHOS Inhibition in High-Risk Neuroblastoma.
PubMed
Paper Journal Title
Cancer Res
Paper Citation Count
31
Paper Publication Year
2021
Bio Mention
-ketoglutarate, -ketoglutarate (KG) dehydrogenase complex, DLST, E2, High, High-Risk Neuroblastoma, High-risk neuroblastoma, IACS-010759, MYCN, NADH, S, Tumor, cancers, dihydrolipoamide, dihydrolipoamide S-succinyltransferase, dlst, glutamine, high-, high-risk neuroblastoma, human, human MYCN-amplified neuroblastoma cells, mouse, neuroblastoma, neuroblastoma cells, patients, succinyl-CoA, tricarboxylic acid, tumor, zebrafish
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Author Name
Affiliation
Shizhen Zhu
Mayo Clinic College of Medicine, Mayo Clinic Cancer Center
Alex Look
Dana-Farber Cancer Institute
Mareike Simon
Abramson Family Cancer Research Institute, University of Pennsylvania Perelman School of Medicine
Mareike Simon
University of Pennsylvania
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