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Paper Details

Pharmacologic activation of hepatic farnesoid X receptor prevents parenteral nutrition-associated cholestasis in mice.
Hepatology
13
2022
ATP, ATP binding cassette subfamily B member 4, ATP-binding cassette, ATP-binding cassette subfamily B member 11, ATP-binding cassette subfamily C member 2, Abcb11, Abcb11 promoter, Abcb4, Abcc2, Abcg5/8, C motif chemokine receptor 2, C-, CONCLUSIONS GW4064, FXR, FXR canonical targets, Fgf15, GW4064, IL-1, Intestinal inflammation, Nr1h4, PNAC, activated hepatic macrophages, bile acids, bile salt, cholestasis, farnesoid, genes, hepatic FXR, hepatic farnesoid X receptor, hepatic injury, hepatic macrophage, hepatocellular, hepatocyte farnesoid X receptor, ileal mRNAs, inflammation, integrin subunit alpha M, intestinal failure, intestinal injury, ll-1b, lymphocyte antigen 6 complex locus C, mRNA, macrophage, mice, mouse, organic solute transporter alpha, patients, phytosterol, primary mouse hepatocytes, sodium sulfate, sterol, subfamily G members 5/8, suppressed
Author NameAffiliation
Karim C El KasmiHepatology and NutritionDepartment of PediatricsUniversity of Colorado School of MedicineAuroraColoradoUSA.
Karim C El KasmiPediatric Liver CenterDigestive Health InstituteChildren's Hospital ColoradoAuroraColoradoUSA.
Karim C El Kasmi
Swati GhoshHepatology and NutritionDepartment of PediatricsUniversity of Colorado School of MedicineAuroraColoradoUSA.
Swati GhoshPediatric Liver CenterDigestive Health InstituteChildren's Hospital ColoradoAuroraColoradoUSA.
Aimee L AndersonHepatology and NutritionDepartment of PediatricsUniversity of Colorado School of MedicineAuroraColoradoUSA.
Aimee L AndersonPediatric Liver CenterDigestive Health InstituteChildren's Hospital ColoradoAuroraColoradoUSA.
Michael W DevereauxHepatology and NutritionDepartment of PediatricsUniversity of Colorado School of MedicineAuroraColoradoUSA.
Michael W DevereauxPediatric Liver CenterDigestive Health InstituteChildren's Hospital ColoradoAuroraColoradoUSA.
Angelo D'AlessandroDepartment of Biochemistry and Molecular GeneticsUniversity of Colorado School of MedicineAuroraColoradoUSA.
Angelo D'AlessandroDepartment of Biochemistry and Molecular GeneticsUniversity of Colorado School of MedicineAuroraColoradoUSA.
David J OrlickyDepartment of PathologyUniversity of Colorado School of MedicineAuroraColoradoUSA.
Colin T ShearnHepatology and NutritionDepartment of PediatricsUniversity of Colorado School of MedicineAuroraColoradoUSA.
Colin T ShearnPediatric Liver CenterDigestive Health InstituteChildren's Hospital ColoradoAuroraColoradoUSA.
Ronald J SokolHepatology and NutritionDepartment of PediatricsUniversity of Colorado School of MedicineAuroraColoradoUSA.
Ronald J SokolPediatric Liver CenterDigestive Health InstituteChildren's Hospital ColoradoAuroraColoradoUSA.
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