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Paper Details

Age-of-diagnosis dependent ileal immune intensification and reduced alpha-defensin in older versus younger pediatric Crohn Disease patients despite already established dysbiosis.
Mucosal Immunol
19
2019
-defensin, CD, Crohn Disease, GM-CSF, IFN, IFN-expressing Th1 cells, INF, Paneth, alpha-defensin, defensin, defensins, epithelial antimicrobial -defensins, ileal dysbiosis, ileal gene, ileal gene signature, ileal involvement, immune genes, patients
Author NameAffiliation
Mi-Ok KimCincinnati Children's Hospital Medical Center and the University of Cincinnati College of Medicine
Marla C DubinskyMount Sinai Hospital New York
Bruce J AronowCincinnati Children's Hospital Medical Center and the University of Cincinnati College of Medicine
Bruce J AronowCincinnati Children's Hospital Medical Center and the University of Cincinnati College of Medicine
Curtis HuttenhowerThe Broad Institute of MIT and Harvard
Curtis HuttenhowerHarvard T.H. Chan School of Public Health
Ramnik J XavierThe Broad Institute of MIT and Harvard
Ramnik J XavierMassachusetts General Hospital, Harvard Medical School
Ramnik J XavierThe Broad Institute of MIT and Harvard
Ramnik J XavierMassachusetts General Hospital, Harvard Medical School
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