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Paper Details

Single-Cell RNA Sequencing Reveals Expanded Clones of Islet Antigen-Reactive CD4<sup>+</sup> T Cells in Peripheral Blood of Subjects with Type 1 Diabetes.
J Immunol
54
2017
-activated cells, Ag, Ag-activated cells, CD4, CD4+, CD4+ T, CD4+ T cell, CD4+ memory T cells, IGRP, IGRP peptides, Islet Antigen-Reactive CD4+ T Cells, Single, T cells, T1D, TCR, TCR clonotypes, Type 1 Diabetes, cells, clones, disease-associated cells, individual, islet Ag, islet Ag-reactive CD4+ memory T cells, islet Ag-reactive T cells, single, type 1 diabetes
Adult, CD4-Positive T-Lymphocytes, Clone Cells, Diabetes Mellitus, Type 1, Female, Gene Expression Profiling, Humans, Immunologic Memory, Islets of Langerhans, Lymphocyte Activation, Male, Peptides, Phenotype, Receptors, Antigen, T-Cell, alpha-beta, Sequence Analysis, RNA, Single-Cell Analysis
Author NameAffiliation
Karen CerosalettiBenaroya Research Institute at Virginia Mason
Fariba Barahmand-PourBenaroya Research Institute at Virginia Mason
Junbao YangBenaroya Research Institute at Virginia Mason
Hannah A DeBergBenaroya Research Institute at Virginia Mason
Matthew J DufortBenaroya Research Institute at Virginia Mason
Sara A MurrayBenaroya Research Institute at Virginia Mason
Elisabeth IsraelssonBenaroya Research Institute at Virginia Mason
Cate SpeakeDiabetes Clinical Research Program, Benaroya Research Institute at Virginia Mason
Vivian H GersukBenaroya Research Institute at Virginia Mason
James A EddyBenaroya Research Institute at Virginia Mason
Helena ReijonenDiabetes Clinical Research Program, Benaroya Research Institute at Virginia Mason
Carla J GreenbaumDiabetes Clinical Research Program, Benaroya Research Institute at Virginia Mason
William W KwokBenaroya Research Institute at Virginia Mason
Erik WambreBenaroya Research Institute at Virginia Mason
Martin PrlicFred Hutchinson Cancer Research Center
Raphael GottardoFred Hutchinson Cancer Research Center
Raphael GottardoFred Hutchinson Cancer Research Center
Gerald T Nepom
Peter S LinsleyBenaroya Research Institute at Virginia Mason
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