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Paper Details

Proteasome inhibition disrupts the metabolism of fumarate hydratase- deficient tumors by downregulating p62 and c-Myc.
Sci Rep
9
2019
C-Myc, FH gene, GLS, GLS2, HLRCC, HLRCC cells, Hereditary leiomyomatosis and renal cell carcinoma, Marizomib, c-Myc, fumarate, fumarate hydratase, fumarate hydratase- deficient tumors, glucose, glutaminases, glutamine, lactate, lactate dehydrogenase A, marizomib, p62, patients, pyruvate, type 2 papillary renal cell carcinoma
Author NameAffiliation
Christopher J RickettsCenter for Cancer Research, National Cancer Institute
Ming-Hui WeiCenter for Cancer Research, National Cancer Institute
William Marston LinehanCenter for Cancer Research, National Cancer Institute
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Release 1.2