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Paper Details

ESCRT-dependent STING degradation inhibits steady-state and cGAMP-induced signalling.
Nat Commun
18
2023
ESCRT, ESCRT complex, HGS, STING, Stimulator of interferon genes, UBAP1, UBAP1 mutant, UBE2N, VPS37A, cGAMP, cyclic di-nucleotides, endosomal sorting complex required for transport, fibroblasts, hereditary spastic paraplegia, interferon genes, pathogen- or self-derived DNA, patients, primary monocyte-derived dendritic cells, type I IFN
Author NameAffiliation
Malvina PapanastasiouBroad Institute of MIT and Harvard
Karsten KrugBroad Institute of MIT and Harvard
John G DoenchBroad Institute of MIT and Harvard
Steven A CarrBroad Institute of MIT and Harvard
Steven A CarrBroad Institute of MIT and Harvard
Nir HacohenBroad Institute of MIT and Harvard
Nir HacohenMassachusetts General Hospital, Harvard Medical School
Nir HacohenCenter for Cancer Research, Massachusetts General Hospital
Nir HacohenBroad Institute of MIT and Harvard
Nir HacohenMassachusetts General Hospital, Harvard Medical School
Nir HacohenCenter for Cancer Research, Massachusetts General Hospital
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