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Paper Details

Altered branched-chain α-keto acid metabolism is a feature of NAFLD in individuals with severe obesity.
JCI Insight
15
2022
AML12 hepatocytes, BCAA, BCAAs, BCKA, BCKAs, BCKDH, BCKDK, BCKDK mRNA, NAFLD, NASH, SREBP1, Val, acylcarnitines, amino acids, branched, branched-chain amino acids, ceramides, hepatic BCKDK, hepatic BCKDK mRNA, human, liver, nonalcoholic fatty liver disease, nonalcoholic steatohepatitis, obesity, patients, plasma, steatosis
Author NameAffiliation
Lydia Coulter KweeSarah W. Stedman Nutrition and Metabolism Center and Duke Molecular Physiology Institute, Duke University Medical Center
Aldons J Lusisuniversity of california los angeles
Marie-Claude VohlSante et Societe and Institute of Nutrition and Functional Foods, Universite Laval
Svati H ShahSarah W. Stedman Nutrition and Metabolism Center and Duke Molecular Physiology Institute, Duke University Medical Center
Svati H ShahSarah W. Stedman Nutrition and Metabolism Center and Duke Molecular Physiology Institute, Duke University Medical Center
Christopher B NewgardSarah W. Stedman Nutrition and Metabolism Center and Duke Molecular Physiology Institute, Duke University Medical Center
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Datasets

Release 1.2