Skip to Main Content

Paper Details

Small molecule C381 targets the lysosome to reduce inflammation and ameliorate disease in models of neurodegeneration.
Proc Natl Acad Sci U S A
14
2022
CRISPRi, Lysosomes, SignificanceNeurodegenerative diseases, brain resident cells, inflammation, lysosomal dysfunction, lysosome, lysosomes, neurodegeneration, neurodegenerative diseases
Author NameAffiliation
Betty ChangPalo Alto Veterans Institute for Research
Michael C BassikInstitute for Chemistry, Stanford University
Michael C BassikStanford University
Michael C BassikInstitute for Chemistry, Stanford University
Michael C BassikStanford University
Judith FrydmanStanford University
Judith FrydmanWu Tsai Neurosciences Institute, Stanford University School of Medicine
Judith FrydmanStanford University
Tony Wyss-CorayStanford University
Tony Wyss-CorayWu Tsai Neurosciences Institute, Stanford University School of Medicine
  • 1 - 10

Datasets

Release 1.2