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Paper Details

A perturbed gene network containing PI3K-AKT, RAS-ERK and WNT-β-catenin pathways in leukocytes is linked to ASD genetics and symptom severity.
Nat Neurosci
55
2019
-catenin, AKT, ASD, ERK, PI3K, RAS, WNT, autism spectrum disorder, highly expressed genes, human, human induced pluripotent stem cell-derived neuron models, leukocyte, leukocytes, perturbed gene network, risk genes, toddlers, upstream regulators
Author NameAffiliation
Benjamin P KellmanUniversity of California San Diego
Benjamin P KellmanUniversity of California San Diego
Sarah S MurrayUniversity of California San Diego
Karen PierceUniversity of California San Diego
Eric CourchesneUniversity of California San Diego
Nathan E LewisUniversity of California San Diego
Nathan E LewisNovo Nordisk Foundation Center for Biosustainability, University of California San Diego
Nathan E LewisUniversity of California San Diego
Nathan E LewisUniversity of California San Diego
Nathan E LewisUniversity of California San Diego
Nathan E LewisNovo Nordisk Foundation Center for Biosustainability, University of California San Diego
Nathan E LewisUniversity of California San Diego
Nathan E LewisUniversity of California San Diego
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Release 1.2