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Paper Details

The APC Variant p.Glu1317Gln predisposes to colorectal adenomas by a novel mechanism of relaxing the target for tumorigenic somatic APC mutations.
Human Mutation
4
2009
20 amino acid beta-catenin downregulating repeats, AFAP, APC, APC Variant, APC alleles, APC mutations, Glu1317Gln, amino acid, attenuated familial adenomatous polyposis, beta, c, c.3949G>C, catenin, coinherit p, colorectal adenomas, mutant, p, p.Glu1317Gln, patients, tumors

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