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Paper Details

Predicting In Vivo Efficacy from In Vitro Data: Quantitative Systems Pharmacology Modeling for an Epigenetic Modifier Drug in Cancer.
Clin Transl Sci
12
2020
Cancer, LSD1, ORY-1001, human, in vitro cell culture, lysine, lysine-specific histone demethylase enzyme, tumor, tumor cell
Author NameAffiliation
Mehdi BouhaddouRoche Pharma Research and Early Development
Mehdi BouhaddouIcahn School of Medicine at Mount Sinai
Mehdi BouhaddouUniversity of California san francisco
Mehdi BouhaddouJ. David Gladstone Institutes
Li YuRoche Pharma Research and Early Development
James M GalloIcahn School of Medicine at Mount Sinai
James M GalloUniversity at Buffalo
Marc R BirtwistleIcahn School of Medicine at Mount Sinai
Marc R BirtwistleClemson University
Marc R BirtwistleIcahn School of Medicine at Mount Sinai
Marc R BirtwistleClemson University
Antje-Christine WalzRoche Pharma Research and Early Development
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Release 1.2