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Paper Details

Phenylalanine-tRNA aminoacylation is compromised by ALS/FTD-associated C9orf72 C4G2 repeat RNA.
Nat Commun
2
2023
ALS, ALS/FTD-associated C9orf72 C4G2 repeat RNA, C9orf72, C9orf72 gene, CCCCGG, CCCCGG antisense repeat RNA, FARS, FARSA, FTD, Phenylalanine, amyotrophic lateral sclerosis, antisense RNA, antisense RNA repeats, antisense transcripts, cellular models, charged tRNA, cytosol, frontotemporal dementia, hexanucleotide, hexanucleotide GGGGCC repeat, patient, phenylalanine, phenylalanine-tRNA synthetase (FARS) subunit alpha, sense and, tRNA
Author NameAffiliation
Guy A RouleauMcGill University
Guy A RouleauMontreal Neurological Institute, McGill University
Guy A RouleauMcGill University
Guy A RouleauMontreal Neurological Institute, McGill University
Manuel MayrKing's College London
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