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Paper Details

Exome sequencing identifies rare LDLR and APOA5 alleles conferring risk for myocardial infarction.
Nature
491
2015
APOA5, APOA5 alleles, LDL cholesterol, LDL), LDLR, LDLR and APOA5 alleles, LDLR coding-sequence mutation, MI, Myocardial infarction, apolipoprotein A-V, apolipoprotein C-III, cholesterol, lipoprotein lipase, loci, low-density lipoprotein, low-density lipoprotein (LDL) genes, low-density lipoprotein receptor, myocardial infarction, patients, protein-coding regions, triglyceride, triglycerides
Author NameAffiliation
Ron Do1] Center for Human Genetic Research, Massachusetts General Hospital, USA. [2] Cardiovascular Research Center, Harvard Medical School, Broad Institute
Nathan O StitzielWashington University School of Medicine
Hong-Hee Won1] Center for Human Genetic Research, Massachusetts General Hospital, USA. [2] Cardiovascular Research Center, Harvard Medical School, Broad Institute
Stefano DugaUniversita degli Studi di Milano
Piera Angelica Merlini
Adam KiezunBroad Institute
Martin FarrallUniversity of Oxford
Anuj GoelUniversity of Oxford
Rosanna AsseltaUniversita degli Studi di Milano
Leslie A LangeUniversity of North Carolina
Gina M Peloso1] Center for Human Genetic Research, Massachusetts General Hospital, USA. [2] Cardiovascular Research Center, Harvard Medical School, Broad Institute
Paul L AuerFred Hutchinson Cancer Research Center
Domenico GirelliUniversity of Verona School of Medicine
Nicola MartinelliUniversity of Verona School of Medicine
Deborah N FarlowBroad Institute
Mark A DePristoBroad Institute
Robert RobertsUniversity of Ottawa Heart Institute
Alexandre F R StewartUniversity of Ottawa Heart Institute
Danish SaleheenUniversity of Cambridge
John DaneshUniversity of Cambridge
Stephen E EpsteinMedStar Health Research Institute, Cardiovascular Research Institute
Suthesh SivapalaratnamAcademic Medical Center
Gerard K HovinghAcademic Medical Center
John J P KasteleinAcademic Medical Center
Nilesh J SamaniUniversity of Leicester, and Leicester NIHR Biomedical Research Unit in Cardiovascular Disease, Glenfield Hospital
Heribert SchunkertDZHK (German Research Centre for Cardiovascular Research), Technische Universitat Munchen
Jeanette ErdmannUniversity of Lubeck
Svati H Shah1] Center for Human Genetics, Duke University, USA. [2] Department of Cardiology and Center for Genomic Medicine, Duke University School of Medicine
Svati H Shah1] Center for Human Genetics, Duke University, USA. [2] Department of Cardiology and Center for Genomic Medicine, Duke University School of Medicine
William E KrausDepartment of Cardiology and Center for Genomic Medicine, Duke University School of Medicine
William E KrausDepartment of Cardiology and Center for Genomic Medicine, Duke University School of Medicine
Christopher T JohansenSchulich School of Medicine and Dentistry, Robarts Research Institute, University of Western Ontario
Robert A HegeleSchulich School of Medicine and Dentistry, Robarts Research Institute, University of Western Ontario
Winfried M??rzMannheim Institute of Public Health, Heidelberg University, Germany. [2] Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Graz
Marcus E KleberMannheim Institute of Public Health, Heidelberg University
Andrew D Johnsonand Blood Institute Center for Population Studies
Andrew D Johnsonand Blood Institute Center for Population Studies
Mingyao LiUniversity of Pennsylvania
Myron D GrossUniversity of Minnesota
Yongmei LiuWake Forest University
Themistocles L AssimesStanford University School of Medicine
Ethan M LangeUniversity of North Carolina, USA. [2] Carolina Center for Genome Sciences
Aaron R FolsomUniversity of Minnesota School of Public Health
Herman A TaylorUniversity of Mississippi Medical Center
Herman A TaylorUniversity of Mississippi Medical Center
Oliviero OlivieriUniversity of Verona School of Medicine
Anders HamstenAtherosclerosis Research Unit, and Center for Molecular Medicine, Karolinska Institutet
Robert ClarkeClinical Trial Service Unit and Epidemiological Studies Unit, University of Oxford
Manuel A RivasUniversity of Oxford
Manuel A RivasUniversity of Oxford
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