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Author Details

Mary B Kennedy
California Institute of Technology
1978
91
54
Andrej Sali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
34563643Amplification of neurotoxic HTTex1 assemblies in human neurons.Neurobiol Dis2021
32678848Interactions between calmodulin and neurogranin govern the dynamics of CaMKII as a leaky integrator.PLoS Comput Biol2020
31939740A sex difference in the response of the rodent postsynaptic density to synGAP haploinsufficiency.Elife2020
30593282In memoriam: John Lisman - commentaries on CaMKII as a memory molecule.Mol Brain2018
29913061The Protein Biochemistry of the Postsynaptic Density in Glutamatergic Synapses Mediates Learning in Neural Networks.Biochemistry2018
30049443Phosphorylation of synaptic GTPase-activating protein (synGAP) by polo-like kinase (Plk2) alters the ratio of its GAP activity toward HRas, Rap1 and Rap2 GTPases.Biochem Biophys Res Commun2018
27955862Liquid Phase Transition in the Postsynaptic Density?Trends Biochem Sci2017
28363979Densin-180 Controls the Trafficking and Signaling of L-Type Voltage-Gated Ca<sub>v</sub>1.2 Ca<sup>2+</sup> Channels at Excitatory Synapses.J Neurosci2017
28160757Biochemistry and neuroscience: the twain need to meet.Curr Opin Neurobiol2017
27623146A model for regulation by SynGAP-α1 of binding of synaptic proteins to PDZ-domain 'Slots' in the postsynaptic density.Elife2016
27759561Correction: A model for regulation by SynGAP-α1 of binding of synaptic proteins to PDZ-domain 'Slots' in the postsynaptic density.Elife2016
25533468Phosphorylation of synaptic GTPase-activating protein (synGAP) by Ca2+/calmodulin-dependent protein kinase II (CaMKII) and cyclin-dependent kinase 5 (CDK5) alters the ratio of its GAP activity toward Ras and Rap GTPases.J Biol Chem2015
26500546Computational reconstitution of spine calcium transients from individual proteins.Front Synaptic Neurosci2015
25829303Protein purification using PDZ affinity chromatography.Curr Protoc Protein Sci2015
24607360PDZ affinity chromatography: a general method for affinity purification of proteins based on PDZ domains and their ligands.Protein Expr Purif2014
25254957Multi-state modeling of biomolecules.PLoS Comput Biol2014
23749614Subcellular organization of camkii in rat hippocampal pyramidal neurons.J Comp Neurol2013
24379319Synaptic Signaling in Learning and Memory.Cold Spring Harb Perspect Biol2013
22700469Molecular and behavioral changes associated with adult hippocampus-specific SynGAP1 knockout.Learn Mem2012
22072671Deletion of densin-180 results in abnormal behaviors associated with mental illness and reduces mGluR5 and DISC1 in the postsynaptic density fraction.J Neurosci2011
20168991A dynamic model of interactions of Ca2+, calmodulin, and catalytic subunits of Ca2+/calmodulin-dependent protein kinase II.PLoS Comput Biol2010
20739295The Huntington's disease mutation impairs Huntingtin's role in the transport of NF-κB from the synapse to the nucleus.Hum Mol Genet2010
18995809Conserved and variable regions in the subunits of brain type II Ca2+/calmodulin-dependent protein kinase.Neuron2008
19074040SynGAP regulates steady-state and activity-dependent phosphorylation of cofilin.J Neurosci2008
18769913Detailed state model of CaMKII activation and autophosphorylation.Eur Biophys J2008
18077696Interactions between the NR2B receptor and CaMKII modulate synaptic plasticity and spatial learning.J Neurosci2007
16966599Ca2+/calmodulin-dependent protein kinase II (CaMKII) is activated by calmodulin with two bound calciums.Proc Natl Acad Sci U S A2006
17096593Structural modeling of protein interactions by analogy: application to PSD-95.PLoS Comput Biol2006
15733080A role for synGAP in regulating neuronal apoptosis.Eur J Neurosci2005
15928715Integration of biochemical signalling in spines.Nat Rev Neurosci2005
15808352Spine architecture and synaptic plasticity.Trends Neurosci2005
14970204Regulation of the neuron-specific Ras GTPase-activating protein, synGAP, by Ca2+/calmodulin-dependent protein kinase II.J Biol Chem2004
15470153SynGAP regulates spine formation.J Neurosci2004
12475938Mammalian septins nomenclature.Mol Biol Cell2002
11160423Densin-180 forms a ternary complex with the (alpha)-subunit of Ca2+/calmodulin-dependent protein kinase II and (alpha)-actinin.J Neurosci2001
11230095Presence of both constitutive and inducible forms of heat shock protein 70 in the cerebral cortex and hippocampal synapses.Cereb Cortex2001
11675481Telling tails.Proc Natl Acad Sci U S A2001
10818142Identification of proteins in the postsynaptic density fraction by mass spectrometry.J Neurosci2000
10844027C-Terminal truncation of NR2A subunits impairs synaptic but not extrasynaptic localization of NMDA receptors.J Neurosci2000
10878817Collective nomenclature for LAP proteins.Nat Cell Biol2000
11052931Signal-processing machines at the postsynaptic density.Science2000
11027319Sticking together.Proc Natl Acad Sci U S A2000
10479685Tetanic stimulation leads to increased accumulation of Ca(2+)/calmodulin-dependent protein kinase II via dendritic protein synthesis in hippocampal neurons.J Neurosci1999
9870942Citron binds to PSD-95 at glutamatergic synapses on inhibitory neurons in the hippocampus.J Neurosci1999
10541463On beyond LTP. Long-term potentiation.Learn Mem1999
9592097Hippocampal synaptic plasticity in mice overexpressing an embryonic subunit of the NMDA receptor.J Neurosci1998
10212401Characterization of calcium/calmodulin-dependent protein kinase II activity in the nervous system of the lobster, Panulirus interruptus.Invert Neurosci1998
9620694A synaptic Ras-GTPase activating protein (p135 SynGAP) inhibited by CaM kinase II.Neuron1998
9651538Signal transduction molecules at the glutamatergic postsynaptic membrane.Brain Res Brain Res Rev1998
9185308The postsynaptic density at glutamatergic synapses.Trends Neurosci1997
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Collaborators

Co-authored papers 3
Max-Planck-Institute of Biochemistry
Co-authored papers 2
California Institute of Technology
Co-authored papers 2
University of Vermont
Co-authored papers 2
University of California san francisco
Co-authored papers 2
National Chung Hsing University
Co-authored papers 1
University of California San Francisco
Co-authored papers 1
Co-authored papers 1
VILLUM Center for Bioanalytical Sciences, University of Southern Denmark
Co-authored papers 1
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University of California los angeles
Co-authored papers 1
University of Vermont
Co-authored papers 1
Boston University Chobanian & Avedisian School of Medicine
Co-authored papers 1
Co-authored papers 1
Max-Planck Institute of Biochemistry
Co-authored papers 1
Worcester Polytechnic Institute
Co-authored papers 1
Picower Institute for Learning and Memory, Massachusetts Institute of Technology
Co-authored papers 1
Co-authored papers 1
Howard Hughes Medical Institute
Co-authored papers 1
Co-authored papers 1