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Author Details

Gregory E Merz
University of California san francisco
2012
16
9
Trey Ideker (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36805129Computational pipeline provides mechanistic understanding of Omicron variant of concern neutralizing engineered ACE2 receptor traps.Structure2023
37236970Stacked binding of a PET ligand to Alzheimer's tau paired helical filaments.Nat Commun2023
36399277Aβ and Tau Prions Causing Alzheimer's Disease.Methods Mol Biol2023
35982665Computational pipeline provides mechanistic understanding of Omicron variant of concern neutralizing engineered ACE2 receptor traps.bioRxiv2022
36454879The E46K mutation modulates α-synuclein prion replication in transgenic mice.PLoS Pathog2022
34031651CryoEM and AI reveal a structure of SARS-CoV-2 Nsp2, a multifunctional protein involved in key host processes.Res Sq2021
33853786Fragment binding to the Nsp3 macrodomain of SARS-CoV-2 identified through crystallographic screening and computational docking.Sci Adv2021
34013269CryoEM and AI reveal a structure of SARS-CoV-2 Nsp2, a multifunctional protein involved in key host processes.bioRxiv2021
32817938An ultra-potent synthetic nanobody neutralizes SARS-CoV-2 by locking Spike into an inactive conformation.bioRxiv2020
33060197Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.Science2020
33154106An ultrapotent synthetic nanobody neutralizes SARS-CoV-2 by stabilizing inactive Spike.Science2020
29611807CK1/Doubletime activity delays transcription activation in the circadian clock.Elife2018
30222354Site-Specific Incorporation of a Cu<sup>2+</sup> Spin Label into Proteins for Measuring Distances by Pulsed Dipolar Electron Spin Resonance Spectroscopy.J Phys Chem B2018
25316790Aggregation propensities of superoxide dismutase G93 hotspot mutants mirror ALS clinical phenotypes.Proc Natl Acad Sci U S A2014
25296320Copper-based pulsed dipolar ESR spectroscopy as a probe of protein conformation linked to disease states.Biophys J2014
22345128Stability of single-nucleotide bulge loops embedded in a GAAA RNA hairpin stem.RNA2012
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Collaborators

Axel F Brilot
University of California san francisco
Co-authored papers 7
Alexandrea N Rizo
University of California san francisco
Co-authored papers 7
Sergei Pourmal
University of California san francisco
Co-authored papers 7
Un Seng Chio
University of California san francisco
Co-authored papers 7
Amber M Smith
University of California san francisco
Co-authored papers 7
Huong T Kratochvil
Department of Pharmaceutical Chemistry, University of California-San Francisco
Co-authored papers 6
Aashish Manglik
Department of Pharmaceutical Chemistry, University of California San Francisco
Co-authored papers 5
Kaitlin Schaefer
Department of Pharmaceutical Chemistry, University of California san francisco
Co-authored papers 5
Tanja Kortemme
University of California san francisco
Co-authored papers 5
Danielle L Swaney
J. David Gladstone Institutes
Co-authored papers 5
Kliment A Verba
University of California, University of California San Francisco
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Kaihua Zhang
Henan Normal University
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Raphael Trenker
Cardiovascular Research Institute, University of California San Francisco
Co-authored papers 5
Komal Ishwar Pawar
University of California san francisco
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Meghna Gupta
University of California san francisco
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Oren S Rosenberg
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Caleigh M Azumaya
Fred Hutchinson Cancer Center
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Cristina Puchades
University of California San Francisco (UCSF) School of Medicine
Co-authored papers 5
Christian B Billesb??lle
Department of Pharmaceutical Chemistry, University of California san francisco
Co-authored papers 5
Henry C Nguyen
Shanghai Clinical Research and Trial Center
Co-authored papers 5
Fengbo Zhou
Washington University School of Medicine
Co-authored papers 5
Nevan J Krogan (CM4AI)
University of California San Francisco
Co-authored papers 5
Eric Tse
School of Clinical Medicine, University of Hong Kong
Co-authored papers 4
Ursula Schulze-Gahmen
Gladstone Institute of Virology, Gladstone Institutes San Francisco CA USA .
Co-authored papers 4
Jocelyne Lopez
University of California san francisco
Co-authored papers 4
Jessica K Peters
Department of Pharmaceutical Chemistry, University of California san francisco
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Soumya G Remesh
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Ishan Deshpande
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