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Author Details

Arnulfo Mendoza
National Cancer Institute, National Institutes of Health
2004
45
29
PMIDPaper TitleJournal TitlePublished Year
36824269PTEN phosphatase inhibits metastasis by negatively regulating the Entpd5/IGF1R pathway through ATF6.iScience2023
37616468Inhibition of NAD+-Dependent Metabolic Processes Induces Cellular Necrosis and Tumor Regression in Rhabdomyosarcoma Models.Clin Cancer Res2023
36824269PTEN phosphatase inhibits metastasis by negatively regulating the Entpd5/IGF1R pathway through ATF6.iScience2023
37314923Using the single-cell imaging system and orthotropic footpad injection to establish mouse models for experimental and spontaneous melanoma metastasis.STAR Protoc2023
37616468Inhibition of NAD+-Dependent Metabolic Processes Induces Cellular Necrosis and Tumor Regression in Rhabdomyosarcoma Models.Clin Cancer Res2023
37314923Using the single-cell imaging system and orthotropic footpad injection to establish mouse models for experimental and spontaneous melanoma metastasis.STAR Protoc2023
33158997Rigosertib Induces Mitotic Arrest and Apoptosis in RAS-Mutated Rhabdomyosarcoma and Neuroblastoma.Mol Cancer Ther2021
33158997Rigosertib Induces Mitotic Arrest and Apoptosis in RAS-Mutated Rhabdomyosarcoma and Neuroblastoma.Mol Cancer Ther2021
32371575EWS-FLI1-regulated Serine Synthesis and Exogenous Serine are Necessary for Ewing Sarcoma Cellular Proliferation and Tumor Growth.Mol Cancer Ther2020
32371575EWS-FLI1-regulated Serine Synthesis and Exogenous Serine are Necessary for Ewing Sarcoma Cellular Proliferation and Tumor Growth.Mol Cancer Ther2020
32060262CASZ1 induces skeletal muscle and rhabdomyosarcoma differentiation through a feed-forward loop with MYOD and MYOG.Nat Commun2020
32908120Inhibition of nicotinamide phosphoribosyltransferase (NAMPT) with OT-82 induces DNA damage, cell death, and suppression of tumor growth in preclinical models of Ewing sarcoma.Oncogenesis2020
32060262CASZ1 induces skeletal muscle and rhabdomyosarcoma differentiation through a feed-forward loop with MYOD and MYOG.Nat Commun2020
32908120Inhibition of nicotinamide phosphoribosyltransferase (NAMPT) with OT-82 induces DNA damage, cell death, and suppression of tumor growth in preclinical models of Ewing sarcoma.Oncogenesis2020
30808861Glutamine synthetase is necessary for sarcoma adaptation to glutamine deprivation and tumor growth.Oncogenesis2019
30808861Glutamine synthetase is necessary for sarcoma adaptation to glutamine deprivation and tumor growth.Oncogenesis2019
31431459Targeting Glycolysis through Inhibition of Lactate Dehydrogenase Impairs Tumor Growth in Preclinical Models of Ewing Sarcoma.Cancer Res2019
31416840Targeting the Chromosomal Passenger Complex Subunit INCENP Induces Polyploidization, Apoptosis, and Senescence in Neuroblastoma.Cancer Res2019
31416840Targeting the Chromosomal Passenger Complex Subunit INCENP Induces Polyploidization, Apoptosis, and Senescence in Neuroblastoma.Cancer Res2019
31431459Targeting Glycolysis through Inhibition of Lactate Dehydrogenase Impairs Tumor Growth in Preclinical Models of Ewing Sarcoma.Cancer Res2019
29334376Positively selected enhancer elements endow osteosarcoma cells with metastatic competence.Nat Med2018
29973406MEK inhibition induces MYOG and remodels super-enhancers in RAS-driven rhabdomyosarcoma.Sci Transl Med2018
29334376Positively selected enhancer elements endow osteosarcoma cells with metastatic competence.Nat Med2018
29634688Corrigendum: Positively selected enhancer elements endow osteosarcoma cells with metastatic competence.Nat Med2018
29973406MEK inhibition induces MYOG and remodels super-enhancers in RAS-driven rhabdomyosarcoma.Sci Transl Med2018
29634688Corrigendum: Positively selected enhancer elements endow osteosarcoma cells with metastatic competence.Nat Med2018
28899971Matrix Screen Identifies Synergistic Combination of PARP Inhibitors and Nicotinamide Phosphoribosyltransferase (NAMPT) Inhibitors in Ewing Sarcoma.Clin Cancer Res2017
28899971Matrix Screen Identifies Synergistic Combination of PARP Inhibitors and Nicotinamide Phosphoribosyltransferase (NAMPT) Inhibitors in Ewing Sarcoma.Clin Cancer Res2017
28404949Metabolomics uncovers a link between inositol metabolism and osteosarcoma metastasis.Oncotarget2017
28404949Metabolomics uncovers a link between inositol metabolism and osteosarcoma metastasis.Oncotarget2017
27342399mTOR Inhibition Mitigates Enhanced mRNA Translation Associated with the Metastatic Phenotype of Osteosarcoma Cells In Vivo.Clin Cancer Res2016
27342399mTOR Inhibition Mitigates Enhanced mRNA Translation Associated with the Metastatic Phenotype of Osteosarcoma Cells In Vivo.Clin Cancer Res2016
27608846STA-8666, a novel HSP90 inhibitor/SN-38 drug conjugate, causes complete tumor regression in preclinical mouse models of pediatric sarcoma.Oncotarget2016
27835791The Role of PDGFR-β Activation in Acquired Resistance to IGF-1R Blockade in Preclinical Models of Rhabdomyosarcoma.Transl Oncol2016
27973325Upregulation of Glucose-Regulated Protein 78 in Metastatic Cancer Cells Is Necessary for Lung Metastasis Progression.Neoplasia2016
27608846STA-8666, a novel HSP90 inhibitor/SN-38 drug conjugate, causes complete tumor regression in preclinical mouse models of pediatric sarcoma.Oncotarget2016
27973325Upregulation of Glucose-Regulated Protein 78 in Metastatic Cancer Cells Is Necessary for Lung Metastasis Progression.Neoplasia2016
27835791The Role of PDGFR-β Activation in Acquired Resistance to IGF-1R Blockade in Preclinical Models of Rhabdomyosarcoma.Transl Oncol2016
25925378IGF-1R Inhibition Activates a YES/SFK Bypass Resistance Pathway: Rational Basis for Co-Targeting IGF-1R and Yes/SFK Kinase in Rhabdomyosarcoma.Neoplasia2015
25925378IGF-1R Inhibition Activates a YES/SFK Bypass Resistance Pathway: Rational Basis for Co-Targeting IGF-1R and Yes/SFK Kinase in Rhabdomyosarcoma.Neoplasia2015
26320182Characterization of the metastatic phenotype of a panel of established osteosarcoma cells.Oncotarget2015
26497213Aurora B kinase is a potent and selective target in MYCN-driven neuroblastoma.Oncotarget2015
26320182Characterization of the metastatic phenotype of a panel of established osteosarcoma cells.Oncotarget2015
26497213Aurora B kinase is a potent and selective target in MYCN-driven neuroblastoma.Oncotarget2015
24186204Mitochondrial retrograde signaling induces epithelial-mesenchymal transition and generates breast cancer stem cells.Oncogene2014
24316974Combined SFK/MEK inhibition prevents metastatic outgrowth of dormant tumor cells.J Clin Invest2014
24186204Mitochondrial retrograde signaling induces epithelial-mesenchymal transition and generates breast cancer stem cells.Oncogene2014
24277455Dual targeting of EWS-FLI1 activity and the associated DNA damage response with trabectedin and SN38 synergistically inhibits Ewing sarcoma cell growth.Clin Cancer Res2014
24316974Combined SFK/MEK inhibition prevents metastatic outgrowth of dormant tumor cells.J Clin Invest2014
24277455Dual targeting of EWS-FLI1 activity and the associated DNA damage response with trabectedin and SN38 synergistically inhibits Ewing sarcoma cell growth.Clin Cancer Res2014
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Collaborators

National Cancer Institute, National Institutes of Health
Co-authored papers 28
Osteosarcoma Institute
Co-authored papers 21
Center for Cancer Research, National Cancer Institute
Co-authored papers 11
Center for Cancer Research, National Cancer Institute
Co-authored papers 6
Center for Cancer Research, National Cancer Institute
Co-authored papers 6
Co-authored papers 5
Case Western Reserve University School of Medicine
Co-authored papers 4
Center for Cancer Research, National Cancer Institute
Co-authored papers 4
Center for Biomedical Informatics and Information Technology
Co-authored papers 3
Center for Cancer Research, National Cancer Institute, National Institutes of Health
Co-authored papers 3
National Cancer Institute, National Institutes of Health
Co-authored papers 3
Center for Cancer Research, National Cancer Institute
Co-authored papers 3
Vertex Pharmaceuticals
Co-authored papers 3
Center for Cancer Research, National Cancer Institute, National Institutes of Health
Co-authored papers 3
National Institutes of Health, National Center for Advancing Translational Sciences
Co-authored papers 3
National Center for Advancing Translational Sciences
Co-authored papers 2
IRCCS Istituto Ortopedico Rizzoli
Co-authored papers 2
St. Jude Children's Research Hospital
Co-authored papers 2
Robert J. Tomsich Pathology and Laboratory Medicine Institute, Cleveland Clinic
Co-authored papers 2
Children's Hospital of Philadelphia.
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Altius Institute for Biomedical Sciences
Co-authored papers 2
Leidos Biomedical Research Inc., Frederick National Laboratory for Cancer Research
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Center for Cancer Research, National Institutes of Health
Co-authored papers 1
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National Cancer Institute
Co-authored papers 1
Center for Cancer Research, National Cancer Institute
Co-authored papers 1
Center for Cancer Research, National Cancer Institute-Frederick
Co-authored papers 1