Author details

Full Name

Dieter Egli

Affiliation

ORCID

Career Start Year

2001

Papers

105

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
36980244	ZnT8 Loss of Function Mutation Increases Resistance of Human Embryonic Stem Cell-Derived Beta Cells to Apoptosis in Low Zinc Condition.		2023
37202286	Replication stress in mammalian embryo development, differentiation, and reprogramming.		2023
35918471	Reduced calcium levels and accumulation of abnormal insulin granules in stem cell models of HNF1A deficiency.	Commun Biol	2022
35394024	Comprehensive analysis of DNA replication timing across 184 cell lines suggests a role for MCM10 in replication timing regulation.	Hum Mol Genet	2022
35858625	Replication stress impairs chromosome segregation and preimplantation development in human embryos.	Cell	2022
34810218	Delayed DNA replication in haploid human embryonic stem cells.	Genome Research	2021
33740453	Heritable human genome editing: Research progress, ethical considerations, and hurdles to clinical practice.	Cell	2021
33630762	Bardet-Biedl syndrome proteins regulate intracellular signaling and neuronal function in patient-specific iPSC-derived neurons.	Journal of Clinical Investigation	2021
33529174	Reduced replication fork speed promotes pancreatic endocrine differentiation and controls graft size.	JCI Insight	2021
34858326	Use of Induced Pluripotent Stem Cells to Build Isogenic Systems and Investigate Type 1 Diabetes.	Front Endocrinol (Lausanne)	2021
32673399	Pluripotent stem cells with low differentiation potential contain incompletely reprogrammed DNA replication.	J Cell Biol	2020
32142661	How Safe Are Universal Pluripotent Stem Cells?		2020
31894105	Physiological consequences of transient hyperleptinemia during discrete developmental periods on body weight in mice.	Science Translational Medicine	2020
32230814	Lessons Learned from Somatic Cell Nuclear Transfer.	International Journal of Molecular Sciences	2020
32051230	GLP-1 receptor agonists synergize with DYRK1A inhibitors to potentiate functional human Î² cell regeneration.	Sci Transl Med	2020
32710620	Detection of base analogs incorporated during DNA replication by nanopore sequencing.	Nucleic Acids Research	2020
32763183	How Safe Are Universal Pluripotent Stem Cells?		2020
33125898	Allele-Specific Chromosome Removal after Cas9 Cleavage in Human Embryos.	Cell	2020
30712508	NanoMod: a computational tool to detect DNA modifications using Nanopore long-read sequencing data.	BMC Genomics	2019
30581122	Combined Inhibition of DYRK1A, SMAD, and Trithorax Pathways Synergizes to Induce Robust Replication in Adult Human Beta Cells.		2019
31519700	Murine Perinatal Î²-Cell Proliferation and the Differentiation of Human Stem Cell-Derived Insulin-Expressing Cells Require NEUROD1.		2019
31491396	Distinct Imprinting Signatures and Biased Differentiation of Human Androgenetic and Parthenogenetic Embryonic Stem Cells.		2019
31120862	Induction of Î± cell-restricted Gc in dedifferentiating Î² cells contributes to stress-induced Î²-cell dysfunction.	JCI insight	2019
30899071	Transgenic substitution with Greater Amberjack Seriola dumerili fish insulin 2 in NOD mice reduces beta cell immunogenicity.	Scientific Reports	2019
30728336	Ciliary gene RPGRIP1L is required for hypothalamic arcuate neuron development.	JCI insight	2019
31363085	Stimulation of CRISPR-mediated homology-directed repair by an engineered RAD18 variant.	Nature Communications	2019
29631040	Derivation and characterization of the NIH registry human stem cell line NYSCF100 line under defined feeder-free conditions.	Stem Cell Research	2018
28931519	Î²-Cell Replacement in Mice Using Human Type 1 Diabetes Nuclear Transfer Embryonic Stem Cells.	Diabetes	2018
30503261	Î² Cell Replacement after Gene Editing of a Neonatal Diabetes-Causing Mutation at the Insulin Locus.	Stem Cell Reports	2018
29872942	Compensating human subjects providing oocytes for stem cell research: 9-year experience and outcomes.		2018
30192441	Pancreatic Beta Cell Differentiation From Human Pluripotent Stem Cells.	Current Protocols in Human Genetics	2018
30089924	Inter-homologue repair in fertilized human eggs?	Nature	2018
30082321	Identification and Analysis of Islet Antigen-Specific CD8<sup>+</sup> T Cells with T Cell Libraries.	J Immunol	2018
29730569	Derivation and characterization of the NIH registry human stem cell line NYSCF101 under defined feeder-free conditions.	Stem Cell Research	2018
29781950	Report of the Key Opinion Leaders Meeting on Stem Cell-derived Beta Cells.	Transplantation	2018
29847571	ILDR2 has a negligible role in hepatic steatosis.	PLoS ONE	2018
28242217	Genome Transfer Prevents Fragmentation and Restores Developmental Potential of Developmentally Compromised Postovulatory Aged MouseÂ Oocytes.	Stem Cell Reports	2017
28548589	Tying genetic stability to cell identity.	Cell Cycle	2017
29161648	Derivation and characterization of the NYSCFe003-A human embryonic stem cell line.	Stem Cell Research	2017
27941249	Deficiency in prohormone convertase PC1 impairs prohormone processing in Prader-Willi syndrome.	Journal of Clinical Investigation	2017
28263958	Genomic instability during reprogramming by nuclear transfer is DNA replication dependent.	Nature Cell Biology	2017
28038847	Inconsistency in 'three-parent' IVF study.	Reproductive BioMedicine Online	2017
28132887	PC1/3 Deficiency Impacts Pro-opiomelanocortin Processing in Human Embryonic Stem Cell-Derived Hypothalamic Neurons.	Stem Cell Reports	2017
28094769	iPSC-derived Î² cells model diabetes due to glucokinase deficiency.	J Clin Invest	2017
27789403	Induced pluripotent stem cells (iPSC) created from skin fibroblasts of patients with Prader-Willi syndrome (PWS) retain the molecular signature of PWS.	Stem Cell Research	2016
27064284	Hypomorphism of Fto and Rpgrip1l causes obesity in mice.	J Clin Invest	2016
27385103	Analysis of chromosomal aberrations and recombination by allelic bias in RNA-Seq.	Nature Communications	2016
27367166	Efficient Generation of Hypothalamic Neurons from Human Pluripotent Stem Cells.	Current Protocols in Human Genetics	2016
27212703	Genetic Drift Can Compromise Mitochondrial Replacement by Nuclear Transfer in Human Oocytes.		2016
26982723	Derivation and differentiation of haploid human embryonic stem cells.	Nature	2016