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Author Details

Lawrence W Castellani
1991
71
41
PMIDPaper TitleJournal TitlePublished Year
26067236The genetic architecture of NAFLD among inbred strains of mice.eLife2015
25651185Genetic architecture of insulin resistance in the mouse.2015
25477283PON3 knockout mice are susceptible to obesity, gallstone formation, and atherosclerosis.FASEB Journal2015
25956888Autocrine VEGF maintains endothelial survival through regulation of metabolism and autophagy.J Cell Sci2015
24489659Deficiency of CCAAT/enhancer binding protein-epsilon reduces atherosclerotic lesions in LDLR-/- mice.PLoS ONE2014
23625949Response to Pomozi et al's research commentary.Circ Res2013
23312289Genetic control of obesity and gut microbiota composition in response to high-fat, high-sucrose diet in mice.Cell Metab2013
21807117A systems genetic analysis of high density lipoprotein metabolism and network preservation across mouse models.Biochim Biophys Acta2012
22811557ABCC6 localizes to the mitochondria-associated membrane.Circ Res2012
22805347Genetic control of high density lipoprotein-cholesterol in AcB/BcA recombinant congenic strains of mice.Physiological Genomics2012
22454476LXRα is uniquely required for maximal reverse cholesterol transport and atheroprotection in ApoE-deficient mice.Journal of Lipid Research2012
22010005Systems genetics of susceptibility to obesity-induced diabetes in mice.Physiol Genomics2012
20947826NF-E2-related factor 2 promotes atherosclerosis by effects on plasma lipoproteins and cholesterol transport that overshadow antioxidant protection.Arteriosclerosis, Thrombosis, and Vascular Biology2011
20054062A high-resolution association mapping panel for the dissection of complex traits in mice.Genome Res2010
20482780Treatment with apolipoprotein A-1 mimetic peptide reduces lupus-like manifestations in a murine lupus model of accelerated atherosclerosis.2010
20393148Early hepatic insulin resistance precedes the onset of diabetes in obese C57BLKS-db/db mice.2010
20160197Quantitative trait locus mapping and identification of Zhx2 as a novel regulator of plasma lipid metabolism.Circulation: Cardiovascular Genetics2010
19995791Upstream transcription factor 1 influences plasma lipid and metabolic traits in mice.Hum Mol Genet2010
19815815Chylomicronemia elicits atherosclerosis in mice--brief report.Arteriosclerosis, Thrombosis, and Vascular Biology2010
19270708Validation of candidate causal genes for obesity that affect shared metabolic pathways and networks.Nat Genet2009
19141870Plasma apolipoprotein AV levels in mice are positively associated with plasma triglyceride levels.Journal of Lipid Research2009
19509018Genetic disruption of myostatin reduces the development of proatherogenic dyslipidemia and atherogenic lesions in Ldlr null mice.Diabetes2009
18421434Identification of ALOX5 as a gene regulating adiposity and pancreatic function.Diabetologia2008
18160395Apolipoprotein AII is a regulator of very low density lipoprotein metabolism and insulin resistance.Journal of Biological Chemistry2008
18239070The antiinflammatory cytokine interleukin-1 receptor antagonist protects from high-fat diet-induced hyperglycemia.Endocrinology2008
17259598ApoE-/-Fas-/- C57BL/6 mice: a novel murine model simultaneously exhibits lupus nephritis, atherosclerosis, and osteopenia.Journal of Lipid Research2007
16876491Mass spectral analysis of the apolipoproteins on mouse high density lipoproteins. Detection of post-translational modifications.2006
16873689Impact of chromosome 2 obesity loci on cardiovascular complications of insulin resistance in LDL receptor-deficient C57BL/6 mice.Diabetes2006
16639078Transgenic mice express human MPO -463G/A alleles at atherosclerotic lesions, developing hyperlipidemia and obesity in -463G males.Journal of Lipid Research2006
16200066Integrating genotypic and expression data in a segregating mouse population to identify 5-lipoxygenase as a susceptibility gene for obesity and bone traits.Nat Genet2005
15928243The 3' untranslated region of the lipoprotein lipase gene: haplotype structure and association with post-heparin plasma lipase activity.Journal of Clinical Endocrinology and Metabolism2005
15520447Thioredoxin-interacting protein deficiency disrupts the fasting-feeding metabolic transition.Journal of Lipid Research2005
15126253Coronary vasomotor abnormalities in insulin-resistant individuals.Annals of Internal Medicine2004
15331434Hyplip2, a new gene for combined hyperlipidemia and increased atherosclerosis.Arteriosclerosis, Thrombosis, and Vascular Biology2004
15466364Mechanisms mediating insulin resistance in transgenic mice overexpressing mouse apolipoprotein A-II.Journal of Lipid Research2004
14729860ApoA-II modulates the association of HDL with class B scavenger receptors SR-BI and CD36.Journal of Lipid Research2004
14729567Peroxisome proliferator-activated receptor-gamma coactivator 1alpha (PGC-1alpha) regulates triglyceride metabolism by activation of the nuclear receptor FXR.Genes and Development2004
14727138Dissection of multigenic obesity traits in congenic mouse strains.Mammalian Genome2004
15051828Mice heterozygous for Atp10c, a putative amphipath, represent a novel model of obesity and type 2 diabetes.Journal of Nutrition2004
15047172Effect of macrophage-derived apolipoprotein E on hyperlipidemia and atherosclerosis of LDLR-deficient mice.Biochemical and Biophysical Research Communications2004
12738753Biochemical and genetic association of plasma apolipoprotein A-II levels with familial combined hyperlipidemia.Circulation Research2003
11788471Transgenic expression of cholesterol-7-alpha-hydroxylase prevents atherosclerosis in C57BL/6J mice.Arteriosclerosis, Thrombosis, and Vascular Biology2002
11753387Positional cloning of the combined hyperlipidemia gene Hyplip1.Nature Genetics2002
12135950Decreased atherosclerotic lesion formation in human serum paraoxonase transgenic mice.Circulation2002
12006400Heritability of subclinical atherosclerosis in Latino families ascertained through a hypertensive parent.Arteriosclerosis, Thrombosis, and Vascular Biology2002
11290828In vivo interactions of apoA-II, apoA-I, and hepatic lipase contributing to HDL structure and antiatherogenic functions.Journal of Lipid Research2001
11742857ApoA-II versus ApoA-I: two for one is not always a good deal.Arteriosclerosis, Thrombosis, and Vascular Biology2001
11252174Fine mapping of Hyplip1 and the human homolog, a potential locus for FCHL.Mamm Genome2001
11246886Studies with apolipoprotein A-II transgenic mice indicate a role for HDLs in adiposity and insulin resistance.Diabetes2001
11323427Increased production of apolipoprotein B-containing lipoproteins in the absence of hyperlipidemia in transgenic mice expressing cholesterol 7alpha-hydroxylase.Journal of Biological Chemistry2001
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