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Author Details
Full Name
Mircea Ivan
Affiliation
Indiana University School of Medicine
ORCID
Career Start Year
1993
Papers
80
H Index
40
Expertise
CM4AI Collaborator
PMID
Paper Title
Journal Title
Published Year
34628029
Hypoxia signaling: Challenges and opportunities for cancer therapy.
Semin Cancer Biol
2022
34376225
Ref-1 redox activity alters cancer cell metabolism in pancreatic cancer: exploiting this novel finding as a potential target.
J Exp Clin Cancer Res
2021
33686243
Correction: The nuclear hypoxia-regulated NLUCAT1 long non-coding RNA contributes to an aggressive phenotype in lung adenocarcinoma through regulation of oxidative stress.
Oncogene
2021
31532878
Osteocytic miR21 deficiency improves bone strength independent of sex despite having sex divergent effects on osteocyte viability and bone turnover.
FEBS J
2020
33159065
Publisher Correction: Regulation of cellular sterol homeostasis by the oxygen responsive noncoding RNA lincNORS.
Nat Commun
2020
33318569
HypoxamiR-210 accelerates wound healing in diabetic mice by improving cellular metabolism.
Commun Biol
2020
32958772
Regulation of cellular sterol homeostasis by the oxygen responsive noncoding RNA lincNORS.
Nat Commun
2020
32618367
Glycolysis, via NADH-dependent dimerisation of CtBPs, regulates hypoxia-induced expression of CAIX and stem-like breast cancer cell survival.
FEBS Lett
2020
32639867
Transcriptomic modifications in developmental cardiopulmonary adaptations to chronic hypoxia using a murine model of simulated high-altitude exposure.
Am J Physiol Lung Cell Mol Physiol
2020
32493919
Author Correction: Hypoxia-mediated downregulation of miRNA biogenesis promotes tumour progression.
Nat Commun
2020
31417181
The nuclear hypoxia-regulated NLUCAT1 long non-coding RNA contributes to an aggressive phenotype in lung adenocarcinoma through regulation of oxidative stress.
Oncogene
2019
31383035
Profiling molecular regulators of recurrence in chemorefractory triple-negative breast cancers.
Breast Cancer Res
2019
28793797
The Many Faces of Long Noncoding RNAs in Cancer.
Antioxid Redox Signal
2018
30158520
P38α/JNK signaling restrains erythropoiesis by suppressing Ezh2-mediated epigenetic silencing of Bim.
Nat Commun
2018
29490339
Enteral Arg-Gln Dipeptide Administration Increases Retinal Docosahexaenoic Acid and Neuroprotectin D1 in a Murine Model of Retinopathy of Prematurity.
Invest Ophthalmol Vis Sci
2018
29059153
Nutrient sensor O-GlcNAc transferase controls cancer lipid metabolism via SREBP-1 regulation.
Oncogene
2018
28818868
Erythropoietin stimulates murine and human fibroblast growth factor-23, revealing novel roles for bone and bone marrow.
Haematologica
2017
28317237
Disruption of the Cx43/miR21 pathway leads to osteocyte apoptosis and increased osteoclastogenesis with aging.
Aging Cell
2017
28961236
Transcriptome analysis of hypoxic cancer cells uncovers intron retention in EIF2B5 as a mechanism to inhibit translation.
PLoS Biol
2017
28622522
The EGLN-HIF O<sub>2</sub>-Sensing System: Multiple Inputs and Feedbacks.
Mol Cell
2017
28866430
The role of MicroRNA molecules and MicroRNA-regulating machinery in the pathogenesis and progression of epithelial ovarian cancer.
Gynecol Oncol
2017
26853146
Allele-Specific Reprogramming of Cancer Metabolism by the Long Non-coding RNA CCAT2.
Mol Cell
2016
28934601
Allele-Specific Reprogramming of Cancer Metabolism by the Long Non-coding RNA CCAT2.
Mol Cell
2016
27535970
Regulation of HIF1α under Hypoxia by APE1/Ref-1 Impacts CA9 Expression: Dual Targeting in Patient-Derived 3D Pancreatic Cancer Models.
Mol Cancer Ther
2016
25492865
Apurinic/apyrimidinic endonuclease/redox factor-1 (APE1/Ref-1) redox function negatively regulates NRF2.
J Biol Chem
2015
26322231
Knockout of Vdac1 activates hypoxia-inducible factor through reactive oxygen species generation and induces tumor growth by promoting metabolic reprogramming and inflammation.
Cancer Metab
2015
26073944
Enhancing Hematopoietic Stem Cell Transplantation Efficacy by Mitigating Oxygen Shock.
Cell
2015
24111776
HypoxamiRs and cancer: from biology to targeted therapy.
Antioxid Redox Signal
2014
25587028
Ferroxitosis: a cell death from modulation of oxidative phosphorylation and PKM2-dependent glycolysis in melanoma.
Oncotarget
2014
25351418
Hypoxia promotes stem cell phenotypes and poor prognosis through epigenetic regulation of DICER.
Nat Commun
2014
25351346
Hypoxia-mediated downregulation of miRNA biogenesis promotes tumour progression.
Nat Commun
2014
25157274
Gene Expression Analysis Reveals Distinct Pathways of Resistance to Bevacizumab in Xenograft Models of Human ER-Positive Breast Cancer.
J Cancer
2014
24272361
miR-210: fine-tuning the hypoxic response.
Adv Exp Med Biol
2014
24292813
Characterizing the heterogeneity of triple-negative breast cancers using microdissected normal ductal epithelium and RNA-sequencing.
Breast Cancer Res Treat
2014
23361368
Dichloroacetate reverses the hypoxic adaptation to bevacizumab and enhances its antitumor effects in mouse xenografts.
J Mol Med (Berl)
2013
24336073
miR-16 and miR-26a target checkpoint kinases Wee1 and Chk1 in response to p53 activation by genotoxic stress.
Cell Death Dis
2013
24037088
HINCUTs in cancer: hypoxia-induced noncoding ultraconserved transcripts.
Cell Death Differ
2013
22700681
Targeting the insulin growth factor and the vascular endothelial growth factor pathways in ovarian cancer.
Mol Cancer Ther
2012
21266476
PDGF induced microRNA alterations in cancer cells.
Nucleic Acids Res
2011
21914808
Dihydroceramide-based response to hypoxia.
J Biol Chem
2011
21747757
Post-Transcriptional Control of the Hypoxic Response by RNA-Binding Proteins and MicroRNAs.
Front Mol Neurosci
2011
21700832
Impact of APE1/Ref-1 redox inhibition on pancreatic tumor growth.
Mol Cancer Ther
2011
21360638
miR-210: More than a silent player in hypoxia.
IUBMB Life
2011
21057537
MicroRNA-221/222 confers breast cancer fulvestrant resistance by regulating multiple signaling pathways.
Oncogene
2011
19896977
microRNA: emerging therapeutic targets in acute ischemic diseases.
Pharmacol Ther
2010
20686363
Blockade of FGF signaling: therapeutic promise for ovarian cancer.
Cancer Biol Ther
2010
21034967
microRNAs in cancer: from bench to bedside.
Adv Cancer Res
2010
20436681
MicroRNA-210 regulates mitochondrial free radical response to hypoxia and krebs cycle in cancer cells by targeting iron sulfur cluster protein ISCU.
PLoS One
2010
19141645
MicroRNA regulation of DNA repair gene expression in hypoxic stress.
Cancer Res
2009
19925433
Emerging roles of microRNAs in the molecular responses to hypoxia.
Curr Pharm Des
2009
1 - 50 of 80
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University of Oxford
Co-authored papers
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Co-authored papers
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University of Oxford
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Co-authored papers
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Jiannis Ragoussis
McGill University
Co-authored papers
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Myriam Gorospe
National Institute on Aging (NIA), National Institutes of Health (NIH)
Co-authored papers
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Fang Fang
Co-authored papers
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Wei Zhang
The University of Texas MD Anderson Cancer Center
Co-authored papers
3
Chad V Pecot
University of North Carolina at Chapel Hill
Co-authored papers
3
Elizabeth Koch
University of Toronto
Co-authored papers
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Mats Ljungman
Co-authored papers
2
Toma Tebaldi
Yale Comprehensive Cancer Center, Yale University School of Medicine
Co-authored papers
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Changyu Shen
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Amber Jannasch
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