Skip to Main Content

Author Details

Mircea Ivan
Indiana University School of Medicine
1993
80
40
PMIDPaper TitleJournal TitlePublished Year
34628029Hypoxia signaling: Challenges and opportunities for cancer therapy.Semin Cancer Biol2022
34376225Ref-1 redox activity alters cancer cell metabolism in pancreatic cancer: exploiting this novel finding as a potential target.J Exp Clin Cancer Res2021
33686243Correction: The nuclear hypoxia-regulated NLUCAT1 long non-coding RNA contributes to an aggressive phenotype in lung adenocarcinoma through regulation of oxidative stress.Oncogene2021
31532878Osteocytic miR21 deficiency improves bone strength independent of sex despite having sex divergent effects on osteocyte viability and bone turnover.FEBS J2020
33159065Publisher Correction: Regulation of cellular sterol homeostasis by the oxygen responsive noncoding RNA lincNORS.Nat Commun2020
33318569HypoxamiR-210 accelerates wound healing in diabetic mice by improving cellular metabolism.Commun Biol2020
32958772Regulation of cellular sterol homeostasis by the oxygen responsive noncoding RNA lincNORS.Nat Commun2020
32618367Glycolysis, via NADH-dependent dimerisation of CtBPs, regulates hypoxia-induced expression of CAIX and stem-like breast cancer cell survival.FEBS Lett2020
32639867Transcriptomic modifications in developmental cardiopulmonary adaptations to chronic hypoxia using a murine model of simulated high-altitude exposure.Am J Physiol Lung Cell Mol Physiol2020
32493919Author Correction: Hypoxia-mediated downregulation of miRNA biogenesis promotes tumour progression.Nat Commun2020
31417181The nuclear hypoxia-regulated NLUCAT1 long non-coding RNA contributes to an aggressive phenotype in lung adenocarcinoma through regulation of oxidative stress.Oncogene2019
31383035Profiling molecular regulators of recurrence in chemorefractory triple-negative breast cancers.Breast Cancer Res2019
28793797The Many Faces of Long Noncoding RNAs in Cancer.Antioxid Redox Signal2018
30158520P38α/JNK signaling restrains erythropoiesis by suppressing Ezh2-mediated epigenetic silencing of Bim.Nat Commun2018
29490339Enteral Arg-Gln Dipeptide Administration Increases Retinal Docosahexaenoic Acid and Neuroprotectin D1 in a Murine Model of Retinopathy of Prematurity.Invest Ophthalmol Vis Sci2018
29059153Nutrient sensor O-GlcNAc transferase controls cancer lipid metabolism via SREBP-1 regulation.Oncogene2018
28818868Erythropoietin stimulates murine and human fibroblast growth factor-23, revealing novel roles for bone and bone marrow.Haematologica2017
28317237Disruption of the Cx43/miR21 pathway leads to osteocyte apoptosis and increased osteoclastogenesis with aging.Aging Cell2017
28961236Transcriptome analysis of hypoxic cancer cells uncovers intron retention in EIF2B5 as a mechanism to inhibit translation.PLoS Biol2017
28622522The EGLN-HIF O<sub>2</sub>-Sensing System: Multiple Inputs and Feedbacks.Mol Cell2017
28866430The role of MicroRNA molecules and MicroRNA-regulating machinery in the pathogenesis and progression of epithelial ovarian cancer.Gynecol Oncol2017
26853146Allele-Specific Reprogramming of Cancer Metabolism by the Long Non-coding RNA CCAT2.Mol Cell2016
28934601Allele-Specific Reprogramming of Cancer Metabolism by the Long Non-coding RNA CCAT2.Mol Cell2016
27535970Regulation of HIF1α under Hypoxia by APE1/Ref-1 Impacts CA9 Expression: Dual Targeting in Patient-Derived 3D Pancreatic Cancer Models.Mol Cancer Ther2016
25492865Apurinic/apyrimidinic endonuclease/redox factor-1 (APE1/Ref-1) redox function negatively regulates NRF2.J Biol Chem2015
26322231Knockout of Vdac1 activates hypoxia-inducible factor through reactive oxygen species generation and induces tumor growth by promoting metabolic reprogramming and inflammation.Cancer Metab2015
26073944Enhancing Hematopoietic Stem Cell Transplantation Efficacy by Mitigating Oxygen Shock.Cell2015
24111776HypoxamiRs and cancer: from biology to targeted therapy.Antioxid Redox Signal2014
25587028Ferroxitosis: a cell death from modulation of oxidative phosphorylation and PKM2-dependent glycolysis in melanoma.Oncotarget2014
25351418Hypoxia promotes stem cell phenotypes and poor prognosis through epigenetic regulation of DICER.Nat Commun2014
25351346Hypoxia-mediated downregulation of miRNA biogenesis promotes tumour progression.Nat Commun2014
25157274Gene Expression Analysis Reveals Distinct Pathways of Resistance to Bevacizumab in Xenograft Models of Human ER-Positive Breast Cancer.J Cancer2014
24272361miR-210: fine-tuning the hypoxic response.Adv Exp Med Biol2014
24292813Characterizing the heterogeneity of triple-negative breast cancers using microdissected normal ductal epithelium and RNA-sequencing.Breast Cancer Res Treat2014
23361368Dichloroacetate reverses the hypoxic adaptation to bevacizumab and enhances its antitumor effects in mouse xenografts.J Mol Med (Berl)2013
24336073miR-16 and miR-26a target checkpoint kinases Wee1 and Chk1 in response to p53 activation by genotoxic stress.Cell Death Dis2013
24037088HINCUTs in cancer: hypoxia-induced noncoding ultraconserved transcripts.Cell Death Differ2013
22700681Targeting the insulin growth factor and the vascular endothelial growth factor pathways in ovarian cancer.Mol Cancer Ther2012
21266476PDGF induced microRNA alterations in cancer cells.Nucleic Acids Res2011
21914808Dihydroceramide-based response to hypoxia.J Biol Chem2011
21747757Post-Transcriptional Control of the Hypoxic Response by RNA-Binding Proteins and MicroRNAs.Front Mol Neurosci2011
21700832Impact of APE1/Ref-1 redox inhibition on pancreatic tumor growth.Mol Cancer Ther2011
21360638miR-210: More than a silent player in hypoxia.IUBMB Life2011
21057537MicroRNA-221/222 confers breast cancer fulvestrant resistance by regulating multiple signaling pathways.Oncogene2011
19896977microRNA: emerging therapeutic targets in acute ischemic diseases.Pharmacol Ther2010
20686363Blockade of FGF signaling: therapeutic promise for ovarian cancer.Cancer Biol Ther2010
21034967microRNAs in cancer: from bench to bedside.Adv Cancer Res2010
20436681MicroRNA-210 regulates mitochondrial free radical response to hypoxia and krebs cycle in cancer cells by targeting iron sulfur cluster protein ISCU.PLoS One2010
19141645MicroRNA regulation of DNA repair gene expression in hypoxic stress.Cancer Res2009
19925433Emerging roles of microRNAs in the molecular responses to hypoxia.Curr Pharm Des2009
  • 1 - 50 of 80

Recommended Authors

The Francis Crick Institute
Career Start Year 2008
Number of shared co-authors 4
Institute of Pathology, Medical University of Innsbruck
Career Start Year 2007
Number of shared co-authors 2
Institute of Neuropathology, Heinrich-Heine University Dusseldorf
Career Start Year 2006
Number of shared co-authors 0
Cancer Science Institute of Singapore, National University of Singapore
Career Start Year 2005
Number of shared co-authors 0
National Institute for Health Research Biomedical Research Centre
Career Start Year 2004
Number of shared co-authors 4
College of Health and Life Sciences, Hamad Bin Khalifa University, Qatar Foundation
Career Start Year 2004
Number of shared co-authors 1
University of Tennessee Health Science Center
Career Start Year 2004
Number of shared co-authors 2
International Centre for Genetic Engineering and Biotechnology
Career Start Year 2004
Number of shared co-authors 1
The University of Hong Kong
Career Start Year 2003
Number of shared co-authors 0
The Wistar Institute
Career Start Year 2003
Number of shared co-authors 1
Ben-Gurion University of the Negev
Career Start Year 2002
Number of shared co-authors 0
University of Udine
Career Start Year 2002
Number of shared co-authors 0
National Institute on Aging, National Institutes of Health
Career Start Year 2002
Number of shared co-authors 4
Mossakowski Medical Research Institute, Polish Academy of Sciences
Career Start Year 1999
Number of shared co-authors 0
Medical Center - University of Freiburg, University of Freiburg
Career Start Year 1999
Number of shared co-authors 1
Beatson Cancer Research Institute, University of Glasgow
Career Start Year 1998
Number of shared co-authors 1
Department of Neurosurgery at the University of Texas MD Anderson Cancer Center
Career Start Year 1998
Number of shared co-authors 0
The University of Texas MD Anderson Cancer Center
Career Start Year 1998
Number of shared co-authors 3
University of Alabama at Birmingham
Career Start Year 1997
Number of shared co-authors 0
Memorial Sloan Kettering Cancer Center
Career Start Year 1996
Number of shared co-authors 4
Quantitative Biosciences Institute (QBI), University of California San Francisco
Career Start Year 1996
Number of shared co-authors 1
Radboud University Medical Center
Career Start Year 1993
Number of shared co-authors 10
Broad Institute of MIT and Harvard
Career Start Year 1989
Number of shared co-authors 3
Candiolo Cancer Institute, Fondazione del Piemonte per l'Oncologia (FPO) - IRCCS
Career Start Year 1988
Number of shared co-authors 1
Netherlands Cancer Institute
Career Start Year 1987
Number of shared co-authors 1
The University of Texas MD Anderson Cancer Center
Career Start Year 1987
Number of shared co-authors 1
Cancer Center, Sanford Burnham Prebys Medical Discovery Institute
Career Start Year 1981
Number of shared co-authors 2
Abramson Family Cancer Research Institute, Perelman School of Medicine
Career Start Year 1980
Number of shared co-authors 2
Broad Institute of MIT and Harvard
Career Start Year 1979
Number of shared co-authors 0
Johns Hopkins University School of Medicine
Career Start Year 1978
Number of shared co-authors 3

Collaborators

The University of Texas MD Anderson Cancer Center
Co-authored papers 10
Garvan Institute of Medical Research
Co-authored papers 9
University of Oxford
Co-authored papers 4
The Wistar Institute
Co-authored papers 4
Harvard Medical School, Beth Israel Deaconess Medical Center
Co-authored papers 3
University of Oxford
Co-authored papers 3
The University of Texas MD Anderson Cancer Center
Co-authored papers 3
Princess Margaret Cancer Centre, University Health Network and, University of Toronto
Co-authored papers 3
McGill University
Co-authored papers 3
National Institute on Aging (NIA), National Institutes of Health (NIH)
Co-authored papers 3
Co-authored papers 3
The University of Texas MD Anderson Cancer Center
Co-authored papers 3
University of North Carolina at Chapel Hill
Co-authored papers 3
University of Toronto
Co-authored papers 3
Co-authored papers 2
Yale Comprehensive Cancer Center, Yale University School of Medicine
Co-authored papers 2
College of Materials Science and Engineering, Zhengzhou University
Co-authored papers 2
Purdue University
Co-authored papers 2
The University of Texas MD Anderson Cancer Center
Co-authored papers 2
Co-authored papers 2
Children's Hospital of Philadelphia
Co-authored papers 2
Memorial Sloan Kettering Cancer Center
Co-authored papers 2
University of Texas MD Anderson Cancer Center
Co-authored papers 2
MD Anderson Cancer Center
Co-authored papers 2
University of Pennsylvania - Perelman School of Medicine
Co-authored papers 2
Radboud University Medical Center
Co-authored papers 2
The University of Texas MD Anderson Cancer Center
Co-authored papers 2
The University of Texas MD Anderson Cancer Center
Co-authored papers 2
Maastricht University Medical Centre
Co-authored papers 1
Co-authored papers 1