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Author Details

Kerry Bloom
University of North Carolina at Chapel Hill
1976
192
56
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36854718Adaptive partitioning of a gene locus to the nuclear envelope in Saccharomyces cerevisiae is driven by polymer-polymer phase separation.Nat Commun2023
37085520Publisher Correction: Adaptive partitioning of a gene locus to the nuclear envelope in Saccharomyces cerevisiae is driven by polymer-polymer phase separation.Nat Commun2023
37436802Misregulation of cell cycle-dependent methylation of budding yeast CENP-A contributes to chromosomal instability.Mol Biol Cell2023
35205396Mechanisms of DNA Mobilization and Sequestration.Genes (Basel)2022
35704466Polymer models reveal how chromatin modification can modulate force at the kinetochore.Mol Biol Cell2022
35858349DNA damage reduces heterogeneity and coherence of chromatin motions.Proc Natl Acad Sci U S A2022
34972957Simulating Dynamic Chromosome Compaction: Methods for Bridging In Silico to In Vivo.Methods Mol Biol2022
35179192Shaping centromeres to resist mitotic spindle forces.J Cell Sci2022
33147102R-loops at centromeric chromatin contribute to defects in kinetochore integrity and chromosomal instability in budding yeast.Mol Biol Cell2021
33735169Behavior of dicentric chromosomes in budding yeast.PLoS Genet2021
33502895Performance of deep learning restoration methods for the extraction of particle dynamics in noisy microscopy image sequences.Mol Biol Cell2021
33836082The rDNA is biomolecular condensate formed by polymer-polymer phase separation and is sequestered in the nucleolus by transcription and R-loops.Nucleic Acids Res2021
34432494Cdc7-mediated phosphorylation of Cse4 regulates high-fidelity chromosome segregation in budding yeast.Mol Biol Cell2021
32516654Polymer perspective of genome mobilization.Mutat Res2020
33080019Statistical mechanics of chromosomes: in vivo and in silico approaches reveal high-level organization and structure arise exclusively through mechanical feedback between loop extruders and chromatin substrate properties.Nucleic Acids Res2020
30718362tRNA Genes Affect Chromosome Structure and Function via Local Effects.Mol Cell Biol2019
31835574Common Features of the Pericentromere and Nucleolus.Genes (Basel)2019
31799251AI-Assisted Forward Modeling of Biological Structures.Front Cell Dev Biol2019
31433796Transient crosslinking kinetics optimize gene cluster interactions.PLoS Comput Biol2019
31573359The regulation of chromosome segregation via centromere loops.Crit Rev Biochem Mol Biol2019
31147925Three-Dimensional Thermodynamic Simulation of Condensin as a DNA-Based Translocase.Methods Mol Biol2019
29187574Stu2 uses a 15-nm parallel coiled coil for kinetochore localization and concomitant regulation of the mitotic spindle.Mol Biol Cell2018
30207827Geometric partitioning of cohesin and condensin is a consequence of chromatin loops.Mol Biol Cell2018
30174190A Kinesin-5, Cin8, Recruits Protein Phosphatase 1 to Kinetochores and Regulates Chromosome Segregation.Curr Biol2018
30373818Fork pausing allows centromere DNA loop formation and kinetochore assembly.Proc Natl Acad Sci U S A2018
29408258Cell Division: Single-Cell Physiology Reveals Secrets of Chromosome Condensation.Curr Biol2018
29561844Cdk1 phosphorylation of Esp1/Separase functions with PP2A and Slk19 to regulate pericentric Cohesin and anaphase onset.PLoS Genet2018
28840251Centromere Structure and Function.Prog Mol Subcell Biol2017
28450453Microtubule dynamics drive enhanced chromatin motion and mobilize telomeres in response to DNA damage.Mol Biol Cell2017
28977453Enrichment of dynamic chromosomal crosslinks drive phase separation of the nucleolus.Nucleic Acids Res2017
29167283RotoStep: A Chromosome Dynamics Simulator Reveals Mechanisms of Loop Extrusion.Cold Spring Harb Symp Quant Biol2017
29237741Liberating cohesin from cohesion.Genes Dev2017
28582586Tension sensors reveal how the kinetochore shares its load.Bioessays2017
28760857FBW7 Loss Promotes Chromosomal Instability and Tumorigenesis via Cyclin E1/CDK2-Mediated Phosphorylation of CENP-A.Cancer Res2017
26974660How the kinetochore couples microtubule force and centromere stretch to move chromosomes.Nat Cell Biol2016
26538024ChromoShake: a chromosome dynamics simulator reveals that chromatin loops stiffen centromeric chromatin.Mol Biol Cell2016
27166637Spatial signals link exit from mitosis to spindle position.Elife2016
27226485Polo kinase Cdc5 associates with centromeres to facilitate the removal of centromeric cohesin during mitosis.Mol Biol Cell2016
27257057Entropy gives rise to topologically associating domains.Nucleic Acids Res2016
27128635A Cohesin-Based Partitioning Mechanism Revealed upon Transcriptional Inactivation of Centromere.PLoS Genet2016
26960795SUMO-Targeted Ubiquitin Ligase (STUbL) Slx5 regulates proteolysis of centromeric histone H3 variant Cse4 and prevents its mislocalization to euchromatin.Mol Biol Cell2016
25946564The SUMO deconjugating peptidase Smt4 contributes to the mechanism required for transition from sister chromatid arm cohesion to sister chromatid pericentromere separation.Cell Cycle2015
26384324Inferring Latent States and Refining Force Estimates via Hierarchical Dirichlet Process Modeling in Single Particle Tracking Experiments.PLoS One2015
26283798DNA loops generate intracentromere tension in mitosis.J Cell Biol2015
25833709Pat1 protects centromere-specific histone H3 variant Cse4 from Psh1-mediated ubiquitination.Mol Biol Cell2015
25926702Anniversary of the discovery/isolation of the yeast centromere by Clarke and Carbon.Mol Biol Cell2015
23893718Bending the rules: widefield microscopy and the Abbe limit of resolution.J Cell Physiol2014
25500356Lessons learned from counting molecules: how to lure CENP-A into the kinetochore.Open Biol2014
25482191Polymer models of interphase chromosomes.Nucleus2014
25251850Centromeric heterochromatin: the primordial segregation machine.Annu Rev Genet2014
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Collaborators

Julian Haase
National Cancer Institute
Co-authored papers 21
Paul S Maddox
University of North Carolina at Chapel Hill
Co-authored papers 18
Andrew D Stephens
Co-authored papers 11
James E Haber
Brandeis University
Co-authored papers 4
Mark Winey
University of California davis
Co-authored papers 4
Charles Boone
University of Toronto
Co-authored papers 3
Molly Fitzgerald-Hayes
Co-authored papers 3
Zhaolei Zhang
University of Toronto
Co-authored papers 2
Alessandro Datti
University of Perugia
Co-authored papers 2
Stephen W Michnick
Co-authored papers 2
Zhijian Li
University of Toronto
Co-authored papers 2
Frederick S Vizeacoumar
College of Medicine, University of Saskatchewan
Co-authored papers 2
Fran??ois Robert
Institut de recherches cliniques de Montreal
Co-authored papers 2
Franco J Vizeacoumar
College of Medicine, University of Saskatchewan
Co-authored papers 2
Brenda J Andrews
University of Toronto
Co-authored papers 2
Michael Costanzo
Co-authored papers 2
Trisha N Davis
University of Washington
Co-authored papers 2
Gary H Karpen
University of California Berkeley
Co-authored papers 2
Sondra Bahr
University of Toronto, College Street
Co-authored papers 1
Qiuqin Wu
Brandeis University
Co-authored papers 1
Nevan J Krogan (CM4AI)
University of California San Francisco
Co-authored papers 1
Jeffrey R Johnson
Gladstone Institutes
Co-authored papers 1
Kevan M Shokat
University of California San Francisco
Co-authored papers 1
Robert C Murphy
Co-authored papers 1
Anne-Claude Gingras
Lunenfeld-Tanenbaum Research Institute
Co-authored papers 1
Carole Doré
Co-authored papers 1
David S Myers
Co-authored papers 1
Brendan J Frey
University of Toronto
Co-authored papers 1
Chandra L Theesfeld
Lewis-Sigler Institute for Integrative Genomics, Princeton University
Co-authored papers 1
Thomas S Hays
University of Minnesota
Co-authored papers 1
Release 1.2