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Author Details

Jonathan S Gootenberg
McGovern Institute for Brain Research at MIT Massachusetts Institute of Technology
2013
58
33
Prashant Mali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36302988Programmable eukaryotic protein synthesis with RNA sensors by harnessing ADAR.Nat Biotechnol2023
37756409Programmable RNA-guided DNA endonucleases are widespread in eukaryotes and their viruses.Sci Adv2023
37192099Discovery of Diverse CRISPR-Cas Systems and Expansion of the Genome Engineering Toolbox.Biochemistry2023
37398409Programmable RNA-guided endonucleases are widespread in eukaryotes and their viruses.bioRxiv2023
36608654A transcription factor atlas of directed differentiation.Cell2023
36424489Drag-and-drop genome insertion of large sequences without double-strand DNA cleavage using CRISPR-directed integrases.Nat Biotechnol2023
36367987A Multiplexed Cas13-Based Assay with Point-of-Care Attributes for Simultaneous COVID-19 Diagnosis and Variant Surveillance.CRISPR J2023
35981511What are the current bottlenecks in developing and applying CRISPR technologies?Cell Syst2022
35643083Structure and engineering of the type III-E CRISPR-Cas7-11 effector complex.Cell2022
36423304RNA-triggered protein cleavage and cell growth arrest by the type III-E CRISPR nuclease-protease.Science2022
36423276RNA-activated protein cleavage with a CRISPR-associated endopeptidase.Science2022
35896753Author Correction: Programmable RNA targeting with the single-protein CRISPR effector Cas7-11.Nature2022
34272525CRISPR-based diagnostics.Nat Biomed Eng2021
33691107High-resolution structure of cas13b and biochemical characterization of RNA targeting and cleavage.Cell Rep2021
34489594Programmable RNA targeting with the single-protein CRISPR effector Cas7-11.Nature2021
34045344CRISPR diagnostics.Science2021
32396992Rapid and accurate species identification for ecological studies and monitoring using CRISPR-based SHERLOCK.Mol Ecol Resour2020
32005984Author Correction: SHERLOCK: nucleic acid detection with CRISPR nucleases.Nat Protoc2020
33137122Rapid SARS-CoV-2 testing in primary material based on a novel multiplex RT-LAMP assay.PLoS One2020
32937062Detection of SARS-CoV-2 with SHERLOCK One-Pot Testing.N Engl J Med2020
32848209Clinical validation of a Cas13-based assay for the detection of SARS-CoV-2 RNA.Nat Biomed Eng2020
32511521Point-of-care testing for COVID-19 using SHERLOCK diagnostics.medRxiv2020
30349047Author Correction: Genome-scale CRISPR-Cas9 knockout and transcriptional activation screening.Nat Protoc2019
31296651A cytosine deaminase for programmable single-base RNA editing.Science2019
31607545Programmable Inhibition and Detection of RNA Viruses Using Cas13.Mol Cell2019
31548639SHERLOCK: nucleic acid detection with CRISPR nucleases.Nat Protoc2019
31371352CRISPR Tools for Systematic Studies of RNA Regulation.Cold Spring Harb Perspect Biol2019
31225754Nucleic Acid Detection of Plant Genes Using CRISPR-Cas13.CRISPR J2019
31036811Structural basis for the promiscuous PAM recognition by Corynebacterium diphtheriae Cas9.Nat Commun2019
30917325High-Resolution Structure of Cas13b and Biochemical Characterization of RNA Targeting and Cleavage.Cell Rep2019
30998093Chipping in on Diagnostics.CRISPR J2019
29700266Field-deployable viral diagnostics using CRISPR-Cas13.Science2018
30166441Engineered CRISPR-Cas9 nuclease with expanded targeting space.Science2018
30054474Pairwise library screen systematically interrogates Staphylococcus aureus Cas9 specificity in human cells.Nat Commun2018
30154463Publisher Correction: Pairwise library screen systematically interrogates Staphylococcus aureus Cas9 specificity in human cells.Nat Commun2018
29449508Multiplexed and portable nucleic acid detection platform with Cas13, Cas12a, and Csm6.Science2018
27918548Multiplex gene editing by CRISPR-Cpf1 using a single crRNA array.Nat Biotechnol2017
28111461Diversity and evolution of class 2 CRISPR-Cas systems.Nat Rev Microbiol2017
28306506Crystal Structure of the Minimal Cas9 from Campylobacter jejuni Reveals the Molecular Diversity in the CRISPR-Cas9 Systems.Mol Cell2017
28408723Nucleic acid detection with CRISPR-Cas13a/C2c2.Science2017
28333914Genome-scale CRISPR-Cas9 knockout and transcriptional activation screening.Nat Protoc2017
28287117Barcode extension for analysis and reconstruction of structures.Nat Commun2017
28178246Erratum: Multiplex gene editing by CRISPR-Cpf1 using a single crRNA array.Nat Biotechnol2017
29070703RNA editing with CRISPR-Cas13.Science2017
28976959RNA targeting with CRISPR-Cas13.Nature2017
28933431Erratum: Genome-scale activation screen identifies a lncRNA locus regulating a gene neighbourhood.Nature2017
28792927Genome-scale activation screen identifies a lncRNA locus regulating a gene neighbourhood.Nature2017
28065598Cas13b Is a Type VI-B CRISPR-Associated RNA-Guided RNase Differentially Regulated by Accessory Proteins Csx27 and Csx28.Mol Cell2017
27054997Corrigendum: Orthogonal gene knockout and activation with a catalytically active Cas9 nuclease.Nat Biotechnol2016
27256883C2c2 is a single-component programmable RNA-guided RNA-targeting CRISPR effector.Science2016
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Collaborators

Omar O Abudayyeh
McGovern Institute for Brain Research at MIT Massachusetts Institute of Technology
Co-authored papers 53
Feng Zhang
Massachusetts Institute of Technology, USA Broad Institute
Co-authored papers 41
David B T Cox
Broad Institute of MIT and Harvard
Co-authored papers 6
Patrick D Hsu
University of California berkeley
Co-authored papers 6
Aviv Regev
Broad Institute of MIT and Harvard
Co-authored papers 5
Cameron Myhrvold
Princeton University
Co-authored papers 5
Eric S Lander
Vanderbilt-Ingram Cancer Center, Vanderbilt University
Co-authored papers 4
James E Dahlman
Georgia Institute of Technology
Co-authored papers 3
Pardis C Sabeti
Harvard University
Co-authored papers 3
Jesse M Engreitz
Co-authored papers 3
François Aguet
Co-authored papers 2
Alexander L Greninger
University of Washington Medical Center
Co-authored papers 2
Charles P Fulco
Co-authored papers 2
Keith R Jerome
Fred Hutchinson Cancer Center
Co-authored papers 2
Bruce D Walker
Ragon Institute of Mass General
Co-authored papers 2
Vic E Myer
Co-authored papers 2
Sourav R Choudhury
Co-authored papers 2
Jesse S Boehm
Broad Institute of Harvard and MIT
Co-authored papers 2
Christopher J Wilson
Co-authored papers 2
Audrone Lapinaite
Arizona State University
Co-authored papers 1
Mamoru Tanaka
Tokyo University of Science
Co-authored papers 1
Soh Ishiguro
The University of British Columbia
Co-authored papers 1
Prashant Mali (CM4AI)
University of California San Diego
Co-authored papers 1
Forest M White
Massachusetts Institute of Technology
Co-authored papers 1
Jordana M Henderson
Co-authored papers 1
Nozomu Yachie
The University of British Columbia
Co-authored papers 1
Alice Y Ting
Stanford University
Co-authored papers 1
Kevin Holden
Synthego Corporation
Co-authored papers 1
Alan S L Wong
The University of Hong Kong
Co-authored papers 1
Ophir Shalem
Perelman School of Medicine, University of Pennsylvania
Co-authored papers 1
Release 1.2