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Author Details

Heather L Howie
University of Virginia School of Medicine.
2004
36
18
Sarah J Ratcliffe (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36373252Identification of multiple genetic loci associated with red blood cell alloimmunization in mice.Haematologica2023
33336414In utero exposure to alloantigens primes alloimmunization to platelet transfusion in mice.Transfusion2021
33777014Antibodies to Low-Copy Number RBC Alloantigen Convert a Tolerogenic Stimulus to an Immunogenic Stimulus in Mice.Front Immunol2021
34480352Mouse background genetics in biomedical research: The devil's in the details.Transfusion2021
34138756Hematologic and systemic metabolic alterations due to Mediterranean class II G6PD deficiency in mice.JCI Insight2021
32289162Passively transferred IgG enhances humoral immunity to a red blood cell alloantigen in mice.Blood Adv2020
31930726IgG3 anti-Kell allotypic variation results in differential antigen binding and phagocytosis.Transfusion2020
32947169Cross-reactivity of mouse IgG subclasses to human Fc gamma receptors: Antibody deglycosylation only eliminates IgG2b binding.Mol Immunol2020
32765523IgG Subclass Determines Suppression Versus Enhancement of Humoral Alloimmunity to Kell RBC Antigens in Mice.Front Immunol2020
32730229Complement activation on endothelium initiates antibody-mediated acute lung injury.J Clin Invest2020
32369193Characterization and refinement of monoclonal anti-human globulins that lack reactivity with human IgG4.Transfusion2020
31350307Differences in Steap3 expression are a mechanism of genetic variation of RBC storage and oxidative damage in mice.Blood Adv2019
29395164Common murine immunoglobulin detection reagents have diminished reactivity with IgG3 - A vulnerability to misinterpretation.J Immunol Methods2018
30169458Murine models of autoimmune hemolytic anemia.Curr Opin Hematol2018
29550761Identification of IgG3-specific epitope that remedies problem in diagnostic IgG subclass determination due to human genetic variation.J Clin Pathol2018
28679954Errors in data interpretation from genetic variation of human analytes.JCI Insight2017
28463043Affinity of human IgG subclasses to mouse Fc gamma receptors.MAbs2017
29163471Innate B-1 B Cells Are Not Enriched in Red Blood Cell Autoimmune Mice: Importance of B Cell Receptor Transgenic Selection.Front Immunol2017
28921569Murine red blood cells from genetically distinct donors cross-regulate when stored together.Transfusion2017
26921359Metabolic pathways that correlate with post-transfusion circulation of stored murine red blood cells.Haematologica2016
27698653Regulatory T Cells Are Dispensable for Tolerance to RBC Antigens.Front Immunol2016
27632931Serological blind spots for variants of human IgG3 and IgG4 by a commonly used anti-immunoglobulin reagent.Transfusion2016
25803638β-HPV 5 and 8 E6 disrupt homology dependent double strand break repair by attenuating BRCA1 and BRCA2 expression and foci formation.PLoS Pathog2015
26053689Analysis of 24-h recovery of transfused stored RBCs in recipient mice of distinct genetic backgrounds.Vox Sang2015
23706308HPV 5 and 8 E6 expression reduces ATM protein levels and attenuates LINE-1 retrotransposition.Virology2013
22301954MYC-driven tumorigenesis is inhibited by WRN syndrome gene deficiency.Mol Cancer Res2012
22807682HPV 5 and 8 E6 abrogate ATR activity resulting in increased persistence of UVB induced DNA damage.PLoS Pathog2012
22623531Functional genomics identifies therapeutic targets for MYC-driven cancer.Proc Natl Acad Sci U S A2012
21901101Beta-HPV 5 and 8 E6 promote p300 degradation by blocking AKT/p300 association.PLoS Pathog2011
19081593Papillomavirus E6 proteins.Virology2009
18391004Extracellular signal-regulated kinase activation by Neisseria gonorrhoeae downregulates epithelial cell proapoptotic proteins Bad and Bim.Infect Immun2008
18715924E6 proteins from multiple human betapapillomavirus types degrade Bak and protect keratinocytes from apoptosis after UVB irradiation.J Virol2008
18256157The E6 oncoproteins from human betapapillomaviruses differentially activate telomerase through an E6AP-dependent mechanism and prolong the lifespan of primary keratinocytes.J Virol2008
15769184The N. gonorrhoeae type IV pilus stimulates mechanosensitive pathways and cytoprotection through a pilT-dependent mechanism.PLoS Biol2005
16137322Expression capable library for studies of Neisseria gonorrhoeae, version 1.0.BMC Microbiol2005
15255894Neisseria meningitidis accelerates ferritin degradation in host epithelial cells to yield an essential iron source.Mol Microbiol2004
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Collaborators

James C Zimring
University of Virginia
Co-authored papers 21
Ariel M Hay
University of Virginia
Co-authored papers 9
Krystalyn E Hudson
Columbia University Irving Medical Center, New York-Presbyterian Hospital
Co-authored papers 9
Arijita Jash
University of Virginia School of Medicine, University of Virginia.
Co-authored papers 3
Angelo D'Alessandro
University of Colorado Anschutz Medical Campus
Co-authored papers 3
Meghan Delaney
Children's National Hospital
Co-authored papers 3
Xiaoyun Fu
College of Forestry, Shenyang Agricultural University
Co-authored papers 3
Steven L Spitalnik
Columbia University Irving Medical Center, New York-Presbyterian Hospital
Co-authored papers 3
Chance John Luckey
University of Virginia School of Medicine.
Co-authored papers 2
Eldad A Hod
Columbia University Irving Medical Center, New York-Presbyterian Hospital
Co-authored papers 2
Tiffany Thomas
Columbia University Irving Medical Center, New York-Presbyterian Hospital
Co-authored papers 1
Sarah J Ratcliffe (CM4AI)
University of Virginia
Co-authored papers 1
Andrey Loboda
Merck & Co., Inc.
Co-authored papers 1
Thomas Brettin
University of Chicago
Co-authored papers 1
Martin Morgan
Roswell Park Comprehensive Cancer Center
Co-authored papers 1
C Ellen van der Schoot
Co-authored papers 1
Pearl Toy
University of California san francisco
Co-authored papers 1
Richard O Francis
Columbia University Irving Medical Center, New York-Presbyterian Hospital
Co-authored papers 1
George M Weinstock
The Genome Center at Washington University, Washington University School of Medicine
Co-authored papers 1
Jeanne E Hendrickson
Center for Transfusion and Cellular Therapy, Emory University School of Medicine
Co-authored papers 1
Larry J Dumont
Vitalant Research Institute
Co-authored papers 1
Erica Sodergren
The Genome Institute at Washington University
Co-authored papers 1
Rachel Culp-Hill
University of Colorado Anschutz Medical Campus
Co-authored papers 1
Mark E Smolkin
University of Virginia
Co-authored papers 1
Aaron N Chang
Baylor College of Medicine
Co-authored papers 1
Mark Smolkin
University of Virginia
Co-authored papers 1
Peter S Linsley
8Benaroya Research Institute
Co-authored papers 1
Release 1.2