Author details

Full Name

Kristin G Ardlie

Affiliation

ORCID

Career Start Year

1996

Papers

131

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37498674	Genetic modification of inflammation- and clonal hematopoiesis-associated cardiovascular risk.	J Clin Invest	2023
37601969	Multiset correlation and factor analysis enables exploration of multi-omics data.	Cell Genom	2023
37662416	Proteome-Wide Association Studies for Blood Lipids and Comparison with Transcriptome-Wide Association Studies.	bioRxiv	2023
37961187	Placental RNA sequencing implicates IGFBP1 in insulin sensitivity during pregnancy and in gestational diabetes.		2023
37869564	Multivariate adaptive shrinkage improves cross-population transcriptome prediction and association studies in underrepresented populations.	HGG Adv	2023
37868038	The functional impact of rare variation across the regulatory cascade.	Cell Genom	2023
37864851	Higher Maternal Body Mass Index is associated with Lower Placental Expression of EPYC: A Genome-Wide Transcriptomic Study.		2023
37770633	Multitissue H3K27ac profiling of GTEx samples links epigenomic variation to disease.	Nat Genet	2023
37216410	Canonical correlation analysis for multi-omics: Application to cross-cohort analysis.	PLoS Genet	2023
36698131	Distinct COPD subtypes in former smokers revealed by gene network perturbation analysis.	Respir Res	2023
37443254	Leveraging polygenic enrichments of gene features to predict genes underlying complex traits and diseases.	Nat Genet	2023
37053313	The origins and functional effects of postzygotic mutations throughout the human life span.	Science	2023
36798214	Multivariate adaptive shrinkage improves cross-population transcriptome prediction for transcriptome-wide association studies in underrepresented populations.	bioRxiv	2023
36993312	Genetic regulation of fetal hemoglobin across global populations.	medRxiv	2023
36463326	Gene expression associations with body mass index in the Multi-Ethnic Study of Atherosclerosis.	Int J Obes (Lond)	2023
37425716	Interaction molecular QTL mapping discovers cellular and environmental modifiers of genetic regulatory effects.	bioRxiv	2023
35100260	Transcription factor regulation of eQTL activity across individuals and tissues.	PLoS Genet	2022
35549429	Single-nucleus cross-tissue molecular reference maps toward understanding disease gene function.	Science	2022
35922509	Transcriptome variation in human tissues revealed by long-read sequencing.	Nature	2022
35716666	Genetic interactions drive heterogeneity in causal variant effect sizes for gene expression and complex traits.	Am J Hum Genet	2022
36777183	The landscape of expression and alternative splicing variation across human traits.	Cell Genom	2022
33499903	Exploiting the GTEx resources to decipher the mechanisms at GWAS loci.	Genome Biol	2021
34015820	Benchmarking association analyses of continuous exposures with RNA-seq in observational studies.	Brief Bioinform	2021
33677499	RNA-SeQC 2: efficient RNA-seq quality control and quantification for large cohorts.	Bioinformatics	2021
33658504	A scalable unified framework of total and allele-specific counts for cis-QTL, fine-mapping, and prediction.	Nature Communications	2021
33057025	Whole genome sequence analysis of pulmonary function and COPD in 19,996 multi-ethnic participants.	Nat Commun	2020
32403949	Transcriptional and Cellular Diversity of the Human Heart.	Circulation	2020
32964524	Fine-mapping and QTL tissue-sharing information improves the reliability of causal gene identification.	Genetic Epidemiology	2020
32913075	Cell type-specific genetic regulation of gene expression across human tissues.	Science	2020
32913074	Determinants of telomere length across human tissues.	Science	2020
32913072	The impact of sex on gene expression across human tissues.	Science	2020
32912332	A vast resource of allelic expression data spanning human tissues.	Genome Biol	2020
32912333	Impact of admixture and ancestry on eQTL analysis and GWAS colocalization in GTEx.	Genome Biol	2020
32912314	sn-spMF: matrix factorization informs tissue-specific genetic regulation of gene expression.	Genome Biol	2020
31171663	RNA sequence analysis reveals macroscopic somatic clonal expansion across normal tissues.	Science	2019
31675989	Scaling computational genomics to millions of individuals with GPUs.	Genome Biol	2019
30559381	Addendum: The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.	Nature	2019
29517003	Corrigendum: Landscape of X chromosome inactivation across human tissues.	Nature	2018
29955180	Using an atlas of gene regulation across 44 human tissues to inform complex disease- and trait-associated variation.	Nat Genet	2018
29440659	The effects of death and post-mortem cold ischemia on human tissue transcriptomes.	Nat Commun	2018
29195078	A Next Generation Connectivity Map: L1000 Platform and the First 1,000,000 Profiles.	Cell	2017
28989986	Data Resources for Human Functional Genomics.	Curr Opin Syst Biol	2017
28846088	Massively parallel single-nucleus RNA-seq with DroNc-seq.	Nat Methods	2017
28714974	Genetic analysis in UK Biobank links insulin resistance and transendothelial migration pathways to coronary artery disease.	Nat Genet	2017
29022598	Landscape of X chromosome inactivation across human tissues.	Nature	2017
26484571	A Novel Approach to High-Quality Postmortem Tissue Procurement: The GTEx Project.	Biopreserv Biobank	2015
25954003	Human genomics. Effect of predicted protein-truncating genetic variants on the human transcriptome.	Science	2015
25954002	Human genomics. The human transcriptome across tissues and individuals.	Science	2015
25970446	Sharing and Specificity of Co-expression Networks across 35 Human Tissues.	PLoS Comput Biol	2015
23622249	Punctuated evolution of prostate cancer genomes.	Cell	2013